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Kcnip1 Gene Detail
Summary
  • Symbol
    Kcnip1
  • Name
    Kv channel-interacting protein 1
  • Synonyms
    2900046L02Rik, 3202002F18Rik, KCHIP1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917607
    NCBI Gene: 70357
  • Gene Overview
    MyGene.info: KCNIP1
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:33629339-33993152 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 19.21 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    891 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917607
protein coding gene Chr11:33629339-33993193 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018147
protein coding gene Chr11:31942691-32325813 (-)
A/J MGP_AJ_G0018120
protein coding gene Chr11:30726254-31096735 (-)
AKR/J MGP_AKRJ_G0018084
protein coding gene Chr11:31685004-32060148 (-)
BALB/cJ MGP_BALBcJ_G0018089
protein coding gene Chr11:30898979-31276544 (-)
C3H/HeJ MGP_C3HHeJ_G0017902
protein coding gene Chr11:31627192-32012006 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018543
protein coding gene Chr11:32974418-33360726 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016198
protein coding gene Chr11:29223484-29581983 (-)
CAST/EiJ MGP_CASTEiJ_G0017466
protein coding gene Chr11:31717552-32119126 (-)
CBA/J MGP_CBAJ_G0017875
protein coding gene Chr11:34582481-35015841 (-)
DBA/2J MGP_DBA2J_G0017985
protein coding gene Chr11:30494347-30864226 (-)
FVB/NJ MGP_FVBNJ_G0017979
protein coding gene Chr11:30317582-30686896 (-)
LP/J MGP_LPJ_G0018057
protein coding gene Chr11:32211273-32597990 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018003
protein coding gene Chr11:35527732-35916175 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018582
protein coding gene Chr11:31835315-32219142 (-)
PWK/PhJ MGP_PWKPhJ_G0017247
protein coding gene Chr11:30682223-31055017 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017039
protein coding gene Chr11:31548869-31952145 (-)
WSB/EiJ MGP_WSBEiJ_G0017515
protein coding gene Chr11:31457214-31852170 (-)



Homology
more
  • Human Ortholog
    KCNIP1, potassium voltage-gated channel interacting protein 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    KCNIP1, potassium voltage-gated channel interacting protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    KCHIP1, VABP
  • Links
    NCBI Gene ID: 30820
    neXtProt AC: NX_Q9NZI2
    UniProt: Q9NZI2

  • Chr Location
    5q35.1; chr5:170353055-170736632 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 22824
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: KCNIP1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit increase susceptibility to pentylenetetrazole-induced seizures.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053519 Ensembl Gene Model | MGI Sequence Detail 363814 C57BL/6J ±  kb
transcript ENSMUST00000109340 Ensembl | MGI Sequence Detail 1840 Not Applicable  
polypeptide ENSMUSP00000104964 Ensembl | MGI Sequence Detail 227 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    cDNA 23
    Primer pair 3

    Microarray probesets 6
Other
Accession IDs
less
MGI:1920202, MGI:2144283, MGI:2144547
References
more
  • Summaries
    All 37
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:239022 Klein AD, et al., Identification of Modifier Genes in a Mouse Model of Gaucher Disease. Cell Rep. 2016 Sep 06;16(10):2546-53

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory