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Iyd
Gene Detail
Symbol

Name
ID
Iyd
iodotyrosine deiodinase
MGI:1917587
Synonyms
0610009A07Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 10
2.06 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr10:3540240-3554877 bp, + strand
From VEGA annotation of GRCm38

  14638 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12352  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Gene Tree: Iyd

Human
homologs
Human Homolog IYD, iodotyrosine deiodinase
NCBI Gene ID 389434
neXtProt AC  NX_Q6PHW0
Human Synonyms  C6orf71, DEHAL1, dJ422F24.1, TDH4
Human Chr (Location)  6q25.1; chr6:150368852-150404629 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human IYD
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Iyd interacts with 85 markers (Mir26a-1, Mir26a-2, Mir26b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process oxidation-reduction process
Component integral component of membrane, membrane
Function iodide peroxidase activity, oxidoreductase activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (17)    Tissues (10)    Images (8)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 17
cDNA source data(28)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(29) cDNA(29)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000027509 (Evidence)
Ensembl Gene ModelENSMUSG00000019762 (Evidence)
Entrez Gene70337 (Evidence)
UniGene24153
DFCITC1583995
DoTSDT.528969
NIA Mouse Gene IndexU011210
EC1.22.1.1
PDB3GFD, 3TNZ, 3GB5, 3GH8, 3TO0
Consensus CDS ProjectCCDS56670.1
International Mouse Knockout Project StatusIyd
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027509 VEGA Gene Model | MGI Sequence Detail 14638 C57BL/6J ±  kb
transcript OTTMUST00000068098 VEGA | MGI Sequence Detail 1579 Not Applicable 
polypeptide OTTMUSP00000034362 VEGA | MGI Sequence Detail 285 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(107 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000415 Nitroreductase-like
Protein Ontology PR:000009170 iodotyrosine dehalogenase 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)
Other
accession IDs
MGI:2143553

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory