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Iyd Gene Detail
Summary
  • Symbol
    Iyd
  • Name
    iodotyrosine deiodinase
  • Synonyms
    0610009A07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917587
    NCBI Gene: 70337
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:3490274-3504880 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 2.06 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    501 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917587
 protein coding gene Chr10:3490240-3504880 (+)
129S1/SvImJ ENSMUSG00200010223
 protein coding gene Chr10:454612-469256 (+)
A/J ENSMUSG00195009904
 protein coding gene Chr10:429536-444182 (+)
AKR/J ENSMUSG00220007294
 protein coding gene Chr10:464810-479454 (+)
BALB/cJ ENSMUSG00180020395
 protein coding gene Chr10:523878-538524 (+)
C3H/HeJ ENSMUSG00175012362
 protein coding gene Chr10:487793-502401 (+)
C57BL/6NJ ENSMUSG00215004523
 protein coding gene Chr10:425113-439748 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015078
 protein coding gene Chr10:325623-340206 (+)
CAST/EiJ ENSTCUG00005017643
 protein coding gene Chr10:504112-518742 (+)
CBA/J ENSMUSG00210012326
 protein coding gene Chr10:436207-450819 (+)
DBA/2J ENSMUSG00185010077
 protein coding gene Chr10:494243-508853 (+)
FVB/NJ ENSMUSG00205007046
 protein coding gene Chr10:468527-483141 (+)
JF1/MsJ ENSUMUG00000033802
 protein coding gene Chr10:633283-647969 (+)
LP/J ENSMUSG00230014649
 protein coding gene Chr10:2123003-2137643 (+)
NOD/ShiLtJ ENSMUSG00190022329
 protein coding gene Chr10:428880-443509 (+)
NZO/HlLtJ ENSMUSG00225013525
 protein coding gene Chr10:6614816-6629474 (+)
PWK/PhJ ENSLUMG00010019289
 protein coding gene Chr10:484095-498698 (+)
SPRET/EiJ ENSMSPG00010006599
 protein coding gene Chr10:638514-652765 (+)
WSB/EiJ ENSIUOG00005013442
 protein coding gene Chr10:482754-497392 (+)



Homology
more
  • Human Ortholog
    IYD, iodotyrosine deiodinase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IYD, iodotyrosine deiodinase
  • Synonyms
    C6orf71, DEHAL1, IYD-1, TDH4
  • Links
    NCBI Gene ID: 389434
    UniProt: Q6PHW0

  • Chr Location
    6q25.1; chr6:150368892-150405969 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human IYD associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    31
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    614
  • Tissues
    10
  • cDNA Data
    29
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 70337 NCBI Gene Model | MGI Sequence Detail 14607 C57BL/6J ±  kb
transcript NM_027391 RefSeq | MGI Sequence Detail 1548 C57BL/6  
polypeptide Q9DCX8 UniProt | EBI | MGI Sequence Detail 285 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 30
    cDNA 30

    Microarray probesets 3
Other
Accession IDs
less
MGI:2143553
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 12
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory