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Iyd Gene Detail
Summary
  • Symbol
    Iyd
  • Name
    iodotyrosine deiodinase
  • Synonyms
    0610009A07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917587
    NCBI Gene: 70337
  • Gene Overview
    MyGene.info: IYD
Location & Maps
more
  • Sequence Map
    Chr10:3540240-3554877 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      14638 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 2.06 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    IYD, iodotyrosine deiodinase
  • Vertebrate Orthologs
    11
  • Human Ortholog
    IYD, iodotyrosine deiodinase
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C6orf71, DEHAL1, IYD-1, TDH4
  • Links
    NCBI Gene ID: 389434
    neXtProt AC: NX_Q6PHW0

  • Chr Location
    6q25.1; chr6:150368861-150404629 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 12352
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;2 zebrafish
  • HCOP
    human homology predictions: IYD
  • Gene Tree
    Iyd
Human Diseases
more
  • Diseases
    1 with human IYD associations

Human Disease Mouse Models
       Thyroid Dyshormonogenesis 4; TDH4   OMIM: 274800
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027509 VEGA Gene Model | MGI Sequence Detail 14638 C57BL/6J ±  kb
transcript OTTMUST00000068098 VEGA | MGI Sequence Detail 1579 Not Applicable  
polypeptide OTTMUSP00000034362 VEGA | MGI Sequence Detail 285 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    103 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 29
    cDNA 29

    Microarray probesets 3
Other
Accession IDs
less
MGI:2143553
References
more
  • Summaries
    All 25
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support.
last database update
08/17/2016
MGI 6.05
The Jackson Laboratory