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Shprh
Gene Detail
Symbol

Name
ID
Shprh
SNF2 histone linker PHD RING helicase
MGI:1917581
Synonyms
2610103K11Rik, D230017O13Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 10
3.66 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr10:11149427-11217595 bp, + strand
From VEGA annotation of GRCm38

  68169 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6489  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Shprh

Human
homologs
Human Homolog SHPRH, SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
NCBI Gene ID 257218
neXtProt AC  NX_Q149N8
Human Synonyms  bA545I5.2
Human Chr (Location)  6q24.3; chr6:145863967-145964285 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(3) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Shprh interacts with 403 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (26 annotations)
Process cellular response to DNA damage stimulus, DNA repair, ...
Component nucleosome, nucleus
Function ATP binding, coenzyme F420-0 gamma-glutamyl ligase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(17)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(21) cDNA(21)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000034163 (Evidence)
Ensembl Gene ModelENSMUSG00000090112 (Evidence)
Entrez Gene268281 (Evidence)
DFCITC1577671, TC1610600, TC1626585, TC1590149
DoTSDT.91335257, DT.91359444, DT.91328925, DT.101737930, DT.40185137, DT.40161808, DT.101264159, DT.101139476, DT.101737929
NIA Mouse Gene IndexU011260
EC6.3.2.-, 3.6.4.-
Consensus CDS ProjectCCDS35838.1, CCDS35839.1, CCDS70003.1
International Mouse Knockout Project StatusShprh
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034163 VEGA Gene Model | MGI Sequence Detail 68169 C57BL/6J ±  kb
transcript OTTMUST00000086593 VEGA | MGI Sequence Detail 9271 Not Applicable 
polypeptide OTTMUSP00000046890 VEGA | MGI Sequence Detail 1674 Not Applicable 

For the selected sequences
All sequences(82) RefSeq(9) UniProt(5)
Polymorphisms
SNPs within 2kb(312 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001650 Helicase, C-terminal
InterPro IPR014001 Helicase, superfamily 1/2, ATP-binding domain
InterPro IPR005818 Histone H1/H5
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR000330 SNF2-related
InterPro IPR011991 Winged helix-turn-helix DNA-binding domain
InterPro IPR011011 Zinc finger, FYVE/PHD-type
InterPro IPR019787 Zinc finger, PHD-finger
InterPro IPR001965 Zinc finger, PHD-type
InterPro IPR019786 Zinc finger, PHD-type, conserved site
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
InterPro IPR001841 Zinc finger, RING-type
Protein Ontology PR:000014852 E3 ubiquitin-protein ligase SHPRH
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(36)
Other
accession IDs
MGI:2441961, MGI:2446137, MGI:3035103, MGI:3035296

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory