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Bclaf1
Gene Detail
 Symbol
Name
ID
Bclaf1
BCL2-associated transcription factor 1
MGI:1917580
Synonyms 2610102K23Rik, 2700025J07Rik, 2810454G14Rik, 5730534O06Rik, mKIAA0164
Feature Type protein coding gene
Genetic Map
Chromosome 10
9.75 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr10:20312469-20342501 bp, + strand
From NCBI annotation of GRCm38

  30033 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8832  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken

Gene Tree: Bclaf1

Human
homologs
Human Homolog BCLAF1, BCL2-associated transcription factor 1
NCBI Gene ID 9774
neXtProt AC  NX_Q9NYF8
Human Synonyms  bK211L9.1, BTF
Human Chr (Location)  6q22-q23; chr6:136256863-136290645 (-)  GRCh38
Alleles
and
phenotypes
All alleles(70) : Gene trapped(65) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit postnatal lethality, impaired lung development, and T cell and B cell homeostasis abnormalities.
 
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process apoptotic process, negative regulation of transcription, DNA-templated, ...
Component cytoplasm, nucleus
Function DNA binding, poly(A) RNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (87)    Tissues (66)    Images (18)
Theiler Stages: 17, 18, 19, 21, 23, 28
Assay TypeResults
RNA in situ 87
cDNA source data(404)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(405) cDNA(405)
Microarray probesets(7)
Other database
links
Ensembl Gene ModelENSMUSG00000037608 (Evidence)
Entrez Gene72567 (Evidence)
UniGene294783
DFCITC1572476, TC1586962, TC1597873, TC1598633, TC1608094, TC1648520
DoTSDT.101180566, DT.101363002, DT.101384106, DT.101711209, DT.103577370, DT.103577371, DT.110593473, DT.55222318, DT.94290376
NIA Mouse Gene IndexU011319
Consensus CDS ProjectCCDS23721.1, CCDS35858.1
International Mouse Knockout Project StatusBclaf1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 72567 NCBI Gene Model | MGI Sequence Detail 30033 C57BL/6J ±  kb
transcript NM_001025392 RefSeq | MGI Sequence Detail 5454 Not Specified 
polypeptide Q8K019 UniProt | EBI | MGI Sequence Detail 919 Not Applicable 

For the selected sequences
All sequences(81) RefSeq(14) UniProt(8)
Polymorphisms SNPs within 2kb(87 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026668 Bcl-2-associated transcription factor 1
Protein Ontology PR:000004706 bcl-2-associated transcription factor 1
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:206963 Orieux G, et al., Involvement of Bcl-2-associated transcription factor 1 in the differentiation of early-born retinal cells. J Neurosci. 2014 Jan 22;34(4):1530-41
All references(48)
Other
accession IDs
MGI:1914501, MGI:1917913, MGI:1919817, MGI:2143607, MGI:2143868

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory