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Bclaf1
Gene Detail
Symbol

Name
ID
Bclaf1
BCL2-associated transcription factor 1
MGI:1917580
Synonyms
2610102K23Rik, 2700025J07Rik, 2810454G14Rik, 5730534O06Rik, mKIAA0164
Feature Type
protein coding gene
Genetic Map
Chromosome 10
9.75 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr10:20312472-20344613 bp, + strand
From VEGA annotation of GRCm38

  32142 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8832  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: BCLAF1
Gene Tree: Bclaf1

Human
homologs
BCLAF1, BCL2-associated transcription factor 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 9774
neXtProt AC: NX_Q9NYF8

Human Synonyms: bK211L9.1, BTF

Human Chr (Location): 6q23.3; chr6:136256863-136290645 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(70) : Gene trapped(65) Targeted(5)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a knock-out allele exhibit postnatal lethality, impaired lung development, and T cell and B cell homeostasis abnormalities.
 
Interactions
Bclaf1 interacts with 351 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process apoptotic process, negative regulation of transcription, DNA-templated, ...
Component cytoplasm, nucleolus, ...
Function DNA binding, poly(A) RNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (87)    Tissues (74)    Images (18)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 87
cDNA source data(404)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase bclaf1    NEW 
Molecular
reagents
All nucleic(405) cDNA(405)
Microarray probesets(7)
Other database
links
VEGA Gene Model OTTMUSG00000049448 (Evidence)
Ensembl Gene Model ENSMUSG00000037608 (Evidence)
Entrez Gene 72567 (Evidence)
UniGene 294783
DFCI TC1586962, TC1608094, TC1572476, TC1598633, TC1597873, TC1648520
DoTS DT.94290376, DT.55222318, DT.103577370, DT.110593473, DT.103577371, DT.101384106, DT.101180566, DT.101363002, DT.101711209
NIA Mouse Gene Index U011319
Consensus CDS Project CCDS23721.1, CCDS35858.1
International Mouse Phenotyping Consortium Status Bclaf1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000049448 VEGA Gene Model | MGI Sequence Detail 32142 C57BL/6J ±  kb
transcript OTTMUST00000126053 VEGA | MGI Sequence Detail 5437 Not Applicable 
polypeptide OTTMUSP00000068204 VEGA | MGI Sequence Detail 919 Not Applicable 

For the selected sequences
All sequences(114) RefSeq(15) UniProt(11)
Polymorphisms
SNPs within 2kb(95 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026668 Bcl-2-associated transcription factor 1
Protein Ontology PR:000004706 bcl-2-associated transcription factor 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:206963 Orieux G, et al., Involvement of Bcl-2-associated transcription factor 1 in the differentiation of early-born retinal cells. J Neurosci. 2014 Jan 22;34(4):1530-41
All references(48)
Other
accession IDs
MGI:1914501, MGI:1917913, MGI:1919817, MGI:2143607, MGI:2143868

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory