Bclaf1
Gene Detail

Symbol

Name
ID

Bclaf1
BCL2-associated transcription factor 1
MGI:1917580

Synonyms

2610102K23Rik, 2700025J07Rik, 2810454G14Rik, 5730534O06Rik, mKIAA0164

Feature Type

protein coding gene

Genetic Map

Chromosome 10
9.75 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr10:20312472-20344613 bp, + strand From VEGA annotation of GRCm38   32142 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:8832  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Gene Tree: Bclaf1

Human
homologs

Human Homolog		BCLAF1, BCL2-associated transcription factor 1
NCBI Gene ID		9774
neXtProt AC		NX_Q9NYF8
Human Synonyms		bK211L9.1, BTF
Human Chr (Location)		6q23.3; chr6:136256863-136290645 (-)  GRCh38

Mutations,
alleles, and
phenotypes

All mutations/alleles(70) : Gene trapped(65) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 

Mice homozygous for a knock-out allele exhibit postnatal lethality, impaired lung development, and T cell and B cell homeostasis abnormalities.

 

Interactions

Bclaf1 interacts with 352 markers (Mir1a-1, Mir1a-2, Mir1b, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (16 annotations)

Process	apoptotic process, negative regulation of transcription, DNA-templated, ...
Component	cytoplasm, nucleolus, ...
Function	DNA binding, poly(A) RNA binding, ...

External Resources: FuncBase

Expression

Literature Summary: (7 records)

Data Summary: Results (87)    Tissues (74)    Images (18)    Tissue x Stage Matrix (view)

Assay Type	Results
RNA in situ	87

cDNA source data(404)
External Resources: Allen Institute   GEO   Expression Atlas

Molecular
reagents

All nucleic(405) cDNA(405)
Microarray probesets(7)

Other database
links

VEGA Gene Model	OTTMUSG00000049448 (Evidence)
Ensembl Gene Model	ENSMUSG00000037608 (Evidence)
Entrez Gene	72567 (Evidence)
UniGene	294783
DFCI	TC1648520, TC1608094, TC1598633, TC1572476, TC1586962, TC1597873
DoTS	DT.55222318, DT.103577371, DT.103577370, DT.110593473, DT.101711209, DT.101384106, DT.101180566, DT.101363002, DT.94290376
NIA Mouse Gene Index	U011319
Consensus CDS Project	CCDS23721.1, CCDS35858.1
International Mouse Knockout Project Status	Bclaf1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000049448	VEGA Gene Model | MGI Sequence Detail	32142	C57BL/6J
transcript	OTTMUST00000126053	VEGA | MGI Sequence Detail	5437	Not Applicable
polypeptide	OTTMUSP00000068204	VEGA | MGI Sequence Detail	919	Not Applicable

All sequences(113) RefSeq(14) UniProt(11)

Polymorphisms

SNPs within 2kb(95 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR026668	Bcl-2-associated transcription factor 1
Protein Ontology	PR:000004706	bcl-2-associated transcription factor 1

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:206963 Orieux G, et al., Involvement of Bcl-2-associated transcription factor 1 in the differentiation of early-born retinal cells. J Neurosci. 2014 Jan 22;34(4):1530-41
All references(49)

Other
accession IDs

MGI:1914501, MGI:1917913, MGI:1919817, MGI:2143607, MGI:2143868