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Gon4l Gene Detail
Summary
  • Symbol
    Gon4l
  • Name
    gon-4-like (C.elegans)
  • Synonyms
    1500041I23Rik, 2610100B20Rik, mKIAA1606
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917579
    NCBI Gene: 76022
  • Gene Overview
    MyGene.info: GON4L
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr3:88835231-88910103 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 39.00 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    270 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917579
protein coding gene Chr3:88830966-88910103 (.)
129S1/SvImJ MGP_129S1SvImJ_G0027409
protein coding gene Chr3:88981445-89076095 (+)
A/J MGP_AJ_G0027373
protein coding gene Chr3:86009865-86146638 (+)
AKR/J MGP_AKRJ_G0027337
protein coding gene Chr3:88074148-88229022 (+)
BALB/cJ MGP_BALBcJ_G0027382
protein coding gene Chr3:86037691-86114585 (+)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0027828
protein coding gene Chr3:92268842-92436713 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025180
protein coding gene Chr3:81559489-81602858 (+)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0027098
protein coding gene Chr3:95495369-95629461 (+)
DBA/2J MGP_DBA2J_G0027236
protein coding gene Chr3:85445867-85524293 (+)
FVB/NJ MGP_FVBNJ_G0027204
protein coding gene Chr3:83698994-83862008 (+)
LP/J MGP_LPJ_G0027345
protein coding gene Chr3:89975539-90179403 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0027887
protein coding gene Chr3:87820287-87976355 (+)
PWK/PhJ MGP_PWKPhJ_G0026304
protein coding gene Chr3:85225676-85394507 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026123
protein coding gene Chr3:87007402-87137655 (+)
WSB/EiJ MGP_WSBEiJ_G0026652
protein coding gene Chr3:88248701-88363267 (+)



Homology
more
  • Human Ortholog
    GON4L, gon-4 like
  • Vertebrate Orthologs
    9
  • Human Ortholog
    GON4L, gon-4 like
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GON4, GON-4, YARP
  • Links
    NCBI Gene ID: 54856
    neXtProt AC: NX_Q3T8J9
    UniProt: Q3T8J9

  • Chr Location
    1q22; chr1:155749658-155859400 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with Gon4l mouse models

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for an ENU-induced allele exhibit arrested B cell development at the early pro-B cell stage.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000054199 Ensembl Gene Model | MGI Sequence Detail 74873 C57BL/6J ±  kb
transcript ENSMUST00000090942 Ensembl | MGI Sequence Detail 7443 Not Applicable  
polypeptide ENSMUSP00000088461 Ensembl | MGI Sequence Detail 2243 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 4
Other
Accession IDs
less
MGI:1916251
References
more
  • Summaries
    All 37
    Diseases 2
    Gene Ontology 6
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:247784 Barr JY, et al., Early B Cell Progenitors Deficient for GON4L Fail To Differentiate Due to a Block in Mitotic Cell Division. J Immunol. 2017 May 15;198(10):3978-3988

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory