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Gcc2 Gene Detail
Summary
  • Symbol
    Gcc2
  • Name
    GRIP and coiled-coil domain containing 2
  • Synonyms
    0610043A03Rik, 2210420P05Rik, 2600014C01Rik, mKIAA0336
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917547
    NCBI Gene: 70297
  • Gene Overview
    MyGene.info: GCC2
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:58255497-58305599 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 29.30 cM, cytoband B3
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    197 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917547
protein coding gene Chr10:58254294-58305599 (.)
129S1/SvImJ MGP_129S1SvImJ_G0017245
protein coding gene Chr10:57340877-57394996 (+)
A/J MGP_AJ_G0017222
protein coding gene Chr10:55690772-55740909 (+)
AKR/J MGP_AKRJ_G0017181
protein coding gene Chr10:57145169-57193716 (+)
BALB/cJ MGP_BALBcJ_G0017183
protein coding gene Chr10:55772175-55821905 (+)
C3H/HeJ MGP_C3HHeJ_G0017006
protein coding gene Chr10:57054893-57106666 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017641
protein coding gene Chr10:59439606-59491169 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015332
protein coding gene Chr10:52805826-52860380 (+)
CAST/EiJ MGP_CASTEiJ_G0016577
protein coding gene Chr10:56971913-57019235 (+)
CBA/J MGP_CBAJ_G0016978
protein coding gene Chr10:61563299-61618961 (+)
DBA/2J MGP_DBA2J_G0017083
protein coding gene Chr10:55018972-55068254 (+)
FVB/NJ MGP_FVBNJ_G0017077
protein coding gene Chr10:54252129-54301447 (+)
LP/J MGP_LPJ_G0017158
protein coding gene Chr10:57736699-57788083 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017105
protein coding gene Chr10:64114611-64176034 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017678
protein coding gene Chr10:56944270-56994657 (+)
PWK/PhJ MGP_PWKPhJ_G0016360
protein coding gene Chr10:54797913-54850030 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016145
protein coding gene Chr10:56313402-56361162 (+)
WSB/EiJ MGP_WSBEiJ_G0016641
protein coding gene Chr10:56848335-56903148 (+)



Homology
more
  • Human Ortholog
    GCC2, GRIP and coiled-coil domain containing 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    GCC2, GRIP and coiled-coil domain containing 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GCC185, RANBP2L4, REN53
  • Links
    NCBI Gene ID: 9648
    neXtProt AC: NX_Q8IWJ2
    UniProt: Q8IWJ2

  • Chr Location
    2q12.3; chr2:108448561-108509398 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 45639
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: GCC2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038039 Ensembl Gene Model | MGI Sequence Detail 50103 C57BL/6J ±  kb
transcript ENSMUST00000057659 Ensembl | MGI Sequence Detail 6547 Not Applicable  
polypeptide ENSMUSP00000054033 Ensembl | MGI Sequence Detail 1680 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    9 Sequences
  • InterPro Domains
    IPR032023 GCC2, Rab binding domain
    IPR000237 GRIP domain
Molecular
Reagents
less
  • All nucleic 85
    cDNA 85

    Microarray probesets 4
Other
Accession IDs
less
MGI:1917423, MGI:1923516, MGI:2143810
References
more
  • Summaries
    All 37
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory