Mkrn2os Gene Detail

Summary

• Symbol
  Mkrn2os
• Name
  makorin, ring finger protein 2, opposite strand
• Synonyms
  2510049J12Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1917541
  NCBI Gene: 70291
• Alliance
  gene page

Location & Maps

• Sequence Map
  Chr6:115583544-115592576 bp, - strand
• From VEGA annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    9033 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 6, 53.60 cM
• Mapping Data
  2 experiments

Homology

• Human Ortholog
  MKRN2OS, MKRN2 opposite strand

• Vertebrate Orthologs
  9

• Human Ortholog
  MKRN2OS, MKRN2 opposite strand
  Orthology source: HomoloGene, HGNC
• Synonyms
  C3orf83, MKRN2-AS1
• Links
  HGNC:40375

  NCBI Gene ID: 100129480

  neXtProt AC: NX_H3BPM6

  UniProt: H3BPM6

  
  
• Chr Location
  3p25.2; chr3:12539713-12561227 (-)  GRCh38.p7

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• HomoloGene
  Vertebrate Homology Class 66298
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 macaque, rhesus
  
• HCOP
  human homology predictions: MKRN2OS
• Gene Tree
  Mkrn2os
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  7 phenotype references
  

• All Mutations and Alleles
  7
• Gene trapped
  2
• Spontaneous
  1
• Targeted
  4
• Genomic Mutations
  1 involving Mkrn2os
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  6 strains or lines available

Expression

• cDNA Data
  10
• Literature Summary
  1

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Interactions

• Mkrn2os interacts with 244 markers (Mir7-1, Mir7-2, Mir10a, ...) View All

Sequences &
Gene Models

• All Sequences
  19
• RefSeq
  2
• UniProt
  2
• CCDS
  CCDS51877.1
• UniGene
  133694

• VEGA
  OTTMUSG00000024488 (Evidence)
• Ensembl
  ENSMUSG00000068011 (Evidence)
• NCBI Gene
  70291

Representative Sequences			Length	Strain/Species
genomic	OTTMUSG00000024488	VEGA Gene Model | MGI Sequence Detail	9033	C57BL/6J
transcript	OTTMUST00000060083	VEGA | MGI Sequence Detail	964	Not Applicable
polypeptide	OTTMUSP00000029288	VEGA | MGI Sequence Detail	217	Not Applicable

Polymorphisms

• SNPs within 2kb
  56 from dbSNP Build 142

Protein
Information

• UniProt
  2 Sequences
• InterPro Domains
  IPR032016 Protein of unknown function DUF4796

Molecular
Reagents

• All nucleic 12

  Genomic 1

  cDNA 11

  
  

  Microarray probesets 1

References

• Summaries
  All 24

  Developmental Gene Expression 1

  Phenotypes 7
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16