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Krt78 Gene Detail
Summary
  • Symbol
    Krt78
  • Name
    keratin 78
  • Synonyms
    2310030B04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917529
    NCBI Gene: 332131
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:101854436-101862722 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 57.15 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    79 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917529
 protein coding gene Chr15:101854436-101905059 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022394
 protein coding gene Chr15:104079005-104086881 (-)
A/J no annotation
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0022360
 protein coding gene Chr15:100046105-100054116 (-)
C3H/HeJ MGP_C3HHeJ_G0022127
 protein coding gene Chr15:103088478-103098393 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022809
 protein coding gene Chr15:107948628-107956506 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020332
 protein coding gene Chr15:95782542-95790566 (-)
CAST/EiJ MGP_CASTEiJ_G0021653
 protein coding gene Chr15:103947967-103955408 (-)
CBA/J MGP_CBAJ_G0022096
 protein coding gene Chr15:111711671-111720654 (-)
DBA/2J MGP_DBA2J_G0022227
 protein coding gene Chr15:99285904-99294054 (-)
FVB/NJ MGP_FVBNJ_G0022203
 protein coding gene Chr15:98343864-98351611 (-)
LP/J MGP_LPJ_G0022296
 protein coding gene Chr15:104234764-104244224 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022225
 protein coding gene Chr15:115328704-115336452 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022821
 protein coding gene Chr15:103047740-103055977 (-)
PWK/PhJ MGP_PWKPhJ_G0021393
 protein coding gene Chr15:99434308-99442228 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021225
 protein coding gene Chr15:102881138-102889023 (-)
WSB/EiJ MGP_WSBEiJ_G0021703
 protein coding gene Chr15:103672431-103680848 (-)



Homology
more
  • Human Ortholog
    KRT78, keratin 78
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRT78, keratin 78
  • Synonyms
    CK-78, K5B, K78, Kb40
  • Links
    NCBI Gene ID: 196374
    neXtProt AC: NX_Q8N1N4
    UniProt: Q8N1N4

  • Chr Location
    12q13.13; chr12:52837804-52848994 (-)  GRCh38.p7
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    27 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    672
  • cDNA Data
    7
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000050463 Ensembl Gene Model | MGI Sequence Detail 8287 C57BL/6J ±  kb
transcript ENSMUST00000164932 Ensembl | MGI Sequence Detail 3437 Not Applicable  
polypeptide ENSMUSP00000126197 Ensembl | MGI Sequence Detail 1068 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR039008 Intermediate filament, rod domain
    IPR003054 Keratin, type II
    IPR032444 Keratin type II head
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 2
References
more
  • Summaries
    All 43
    Diseases 1
    Gene Ontology 2
    Phenotypes 27
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
08/03/2022
MGI 6.21 		The Jackson Laboratory