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Dazap1
Gene Detail
Symbol

Name
ID
Dazap1
DAZ associated protein 1
MGI:1917498
Synonyms
2410042M16Rik, mPrrp
Feature Type
protein coding gene
Genetic Map
Chromosome 10
39.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr10:80261486-80288408 bp, + strand
From VEGA annotation of GRCm38

  26923 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:134440  Vertebrate Homology Class
1 mouse; 1 chicken

Gene Tree: Dazap1

Mutations,
alleles, and
phenotypes
All mutations/alleles(48) : Gene trapped(43) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for a null allele show partial lethality during fetal growth through weaning, growth retardation, spermatogenic arrest, and premature death. Homozygotes for a hypomorphic allele live longer but are small and sterile and display small gonads, spermatogenic arrest, and abnormal pregnancy.
 
Interactions
Dazap1 interacts with 157 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process cell differentiation, cell proliferation, ...
Component cytoplasm, nucleus
Function nucleic acid binding, nucleotide binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (150)    Tissues (129)    Images (28)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 114
Northern blot 8
Western blot 17
RT-PCR 11
cDNA source data(89)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(93) cDNA(89) Primer pair(3) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000000016 (Evidence)
Ensembl Gene ModelENSMUSG00000069565 (Evidence)
Entrez Gene70248 (Evidence)
UniGene148693
DFCITC1575869, TC1595393
DoTSDT.489964
NIA Mouse Gene IndexU059027
Consensus CDS ProjectCCDS35977.1, CCDS48626.1, CCDS48627.1
International Mouse Knockout Project StatusDazap1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000016 VEGA Gene Model | MGI Sequence Detail 26923 C57BL/6J ±  kb
transcript OTTMUST00000045776 VEGA | MGI Sequence Detail 1537 Not Applicable 
polypeptide OTTMUSP00000020614 VEGA | MGI Sequence Detail 406 Not Applicable 

For the selected sequences
All sequences(71) RefSeq(18) UniProt(11)
Polymorphisms
SNPs within 2kb(47 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012677 Nucleotide-binding, alpha-beta plait
InterPro IPR000504 RNA recognition motif domain
Protein Ontology PR:000006288 DAZ-associated protein 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:210719 Chen HY, et al., DAZAP1 regulates the splicing of Crem, Crisp2 and Pot1a transcripts. Nucleic Acids Res. 2013 Nov;41(21):9858-69
All references(42)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory