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Ppil3 Gene Detail
Summary
  • Symbol
    Ppil3
  • Name
    peptidylprolyl isomerase (cyclophilin)-like 3
  • Synonyms
    2310076N22Rik, 2510026K04Rik, Cyp10l
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917475
    NCBI Gene: 70225
  • Gene Overview
    MyGene.info: PPIL3
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:58430994-58445486 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 29.10 cM, cytoband C2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    134 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917475
protein coding gene Chr1:58430993-58445527 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016051
protein coding gene Chr1:58297122-58313164 (-)
A/J MGP_AJ_G0016034
protein coding gene Chr1:56253982-56268239 (-)
AKR/J MGP_AKRJ_G0015990
protein coding gene Chr1:57777146-57792654 (-)
BALB/cJ MGP_BALBcJ_G0015989
protein coding gene Chr1:56291121-56306037 (-)
C3H/HeJ MGP_C3HHeJ_G0015821
protein coding gene Chr1:58044911-58060405 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016442
protein coding gene Chr1:60640054-60654395 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014164
protein coding gene Chr1:52187178-52201190 (-)
CAST/EiJ MGP_CASTEiJ_G0015403
protein coding gene Chr1:57290368-57315780 (-)
CBA/J MGP_CBAJ_G0015793
protein coding gene Chr1:62422614-62441569 (-)
DBA/2J MGP_DBA2J_G0015894
protein coding gene Chr1:55654212-55669052 (-)
FVB/NJ MGP_FVBNJ_G0015896
protein coding gene Chr1:54995884-55010120 (-)
LP/J MGP_LPJ_G0015966
protein coding gene Chr1:59191728-59206691 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015916
protein coding gene Chr1:65425241-65442148 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016489
protein coding gene Chr1:57749396-57765062 (-)
PWK/PhJ MGP_PWKPhJ_G0015189
protein coding gene Chr1:55047195-55061634 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014970
protein coding gene Chr1:57337278-57352001 (-)
WSB/EiJ MGP_WSBEiJ_G0015466
protein coding gene Chr1:57438656-57454563 (-)



Homology
more
  • Human Ortholog
    PPIL3, peptidylprolyl isomerase like 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PPIL3, peptidylprolyl isomerase like 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CYPJ
  • Links
    NCBI Gene ID: 53938
    neXtProt AC: NX_Q9H2H8
    UniProt: Q9H2H8

  • Chr Location
    2q33.1; chr2:200870907-200889333 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    13
  • Chemically induced (other)
    1
  • Gene trapped
    8
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Ppil3
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026035 Ensembl Gene Model | MGI Sequence Detail 14493 C57BL/6J ±  kb
transcript ENSMUST00000117069 Ensembl | MGI Sequence Detail 1363 Not Applicable  
polypeptide ENSMUSP00000112947 Ensembl | MGI Sequence Detail 161 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • EC
  • InterPro Domains
    IPR029000 Cyclophilin-like domain superfamily
    IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase
    IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site
    IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
Molecular
Reagents
less
  • All nucleic 22
    cDNA 22

    Microarray probesets 4
Other
Accession IDs
less
MGI:1917543
References
more
  • Summaries
    All 35
    Gene Ontology 5
    Phenotypes 12
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory