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Lipn Gene Detail
Summary
  • Symbol
    Lipn
  • Name
    lipase, family member N
  • Synonyms
    2210418G03Rik, Lipl4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917416
    NCBI Gene: 70166
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:34067358-34084918 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 29.32 cM, cytoband C3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    177 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917416
protein coding gene Chr19:34067058-34085946 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025051
protein coding gene Chr19:32797692-32819649 (+)
A/J MGP_AJ_G0025029
protein coding gene Chr19:31204984-31223182 (+)
AKR/J MGP_AKRJ_G0024995
protein coding gene Chr19:32256309-32276635 (+)
BALB/cJ MGP_BALBcJ_G0025025
protein coding gene Chr19:31317491-31335768 (+)
C3H/HeJ MGP_C3HHeJ_G0024784
protein coding gene Chr19:32360097-32387533 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025466
protein coding gene Chr19:33742697-33762195 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022884
protein coding gene Chr19:30658522-30675736 (+)
CAST/EiJ MGP_CASTEiJ_G0024254
protein coding gene Chr19:32093713-32122054 (+)
CBA/J MGP_CBAJ_G0024761
protein coding gene Chr19:35324391-35348874 (+)
DBA/2J MGP_DBA2J_G0024893
protein coding gene Chr19:31103986-31124641 (+)
FVB/NJ MGP_FVBNJ_G0024854
protein coding gene Chr19:30951166-30971608 (+)
LP/J MGP_LPJ_G0024979
protein coding gene Chr19:32890613-32912183 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024885
protein coding gene Chr19:35143404-35162903 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025524
protein coding gene Chr19:32352064-32373519 (+)
PWK/PhJ MGP_PWKPhJ_G0024003
protein coding gene Chr19:30917947-30924504 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023804
protein coding gene Chr19:31212711-31232868 (+)
WSB/EiJ MGP_WSBEiJ_G0024318
protein coding gene Chr19:32437111-32456559 (+)



Homology
more
  • Human Ortholog
    LIPN, lipase family member N
  • Vertebrate Orthologs
    7
  • Human Ortholog
    LIPN, lipase family member N
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ARCI8, bA186O14.3, LI4, LIPL4
  • Links
    NCBI Gene ID: 643418
    neXtProt AC: NX_Q5VXI9
    UniProt: Q5VXI9

  • Chr Location
    10q23.31; chr10:88757226-88783662 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human LIPN associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024770 Ensembl Gene Model | MGI Sequence Detail 17561 C57BL/6J ±  kb
transcript ENSMUST00000025682 Ensembl | MGI Sequence Detail 1502 Not Applicable  
polypeptide ENSMUSP00000025682 Ensembl | MGI Sequence Detail 400 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 2
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:246066 Sundberg JP, et al., Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program. PLoS One. 2017;12(7):e0180682

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory