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Lypd8 Gene Detail
Summary
  • Symbol
    Lypd8
  • Name
    LY6/PLAUR domain containing 8
  • Synonyms
    2210415F13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917413
    NCBI Gene: 70163
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:58379032-58390541 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 36.19 cM, cytoband B2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    162 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917413
protein coding gene Chr11:58379032-58390728 (.)
129S1/SvImJ MGP_129S1SvImJ_G0018351
protein coding gene Chr11:58102246-58115044 (+)
A/J MGP_AJ_G0018321
protein coding gene Chr11:55873494-55885163 (+)
AKR/J MGP_AKRJ_G0018290
protein coding gene Chr11:57703358-57715823 (+)
BALB/cJ MGP_BALBcJ_G0018292
protein coding gene Chr11:56210877-56222931 (+)
C3H/HeJ MGP_C3HHeJ_G0018103
protein coding gene Chr11:57647341-57659544 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018743
protein coding gene Chr11:59877907-59891178 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016393
protein coding gene Chr11:53220807-53232215 (+)
CAST/EiJ MGP_CASTEiJ_G0017668
protein coding gene Chr11:57738357-57753661 (+)
CBA/J MGP_CBAJ_G0018078
protein coding gene Chr11:62633531-62645281 (+)
DBA/2J MGP_DBA2J_G0018187
protein coding gene Chr11:55520287-55533794 (+)
FVB/NJ MGP_FVBNJ_G0018178
protein coding gene Chr11:55208195-55220145 (+)
LP/J MGP_LPJ_G0018262
protein coding gene Chr11:58628624-58641021 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018204
protein coding gene Chr11:63732162-63744150 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018786
protein coding gene Chr11:57762102-57773564 (+)
PWK/PhJ MGP_PWKPhJ_G0017440
protein coding gene Chr11:56133680-56151819 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017235
protein coding gene Chr11:57641979-57657371 (+)
WSB/EiJ MGP_WSBEiJ_G0017715
protein coding gene Chr11:57399752-57414877 (+)



Homology
more
  • Human Ortholog
    LYPD8, LY6/PLAUR domain containing 8
  • Vertebrate Orthologs
    7
  • Human Ortholog
    LYPD8, LY6/PLAUR domain containing 8
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 646627
    neXtProt AC: NX_Q6UX82
    UniProt: Q6UX82

  • Chr Location
    1q44; chr1:248739415-248755787 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
No notable phenotype was detected in a high throughput screen of homozygous mice.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 70163 NCBI Gene Model | MGI Sequence Detail 11510 C57BL/6J ±  kb
transcript NM_001083884 RefSeq | MGI Sequence Detail 1122 C57BL/6  
polypeptide Q9D7S0 UniProt | EBI | MGI Sequence Detail 255 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 288
    cDNA 288

    Microarray probesets 3
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:232706 Okumura R, et al., Lypd8 promotes the segregation of flagellated microbiota and colonic epithelia. Nature. 2016 Apr 7;532(7597):117-21

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory