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Dnmbp Gene Detail
Summary
  • Symbol
    Dnmbp
  • Name
    dynamin binding protein
  • Synonyms
    2410003L07Rik, 2410003M15Rik, Tuba
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917352
    NCBI Gene: 71972
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:43846821-43940191 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 36.67 cM, cytoband D1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    736 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917352
protein coding gene Chr19:43846815-43940323 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025159
protein coding gene Chr19:43275832-43376840 (-)
A/J MGP_AJ_G0025136
protein coding gene Chr19:41218482-41293537 (-)
AKR/J MGP_AKRJ_G0025104
protein coding gene Chr19:42512572-42577132 (-)
BALB/cJ MGP_BALBcJ_G0025130
protein coding gene Chr19:41264030-41357365 (-)
C3H/HeJ MGP_C3HHeJ_G0024890
protein coding gene Chr19:42694955-42790471 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025573
protein coding gene Chr19:44343924-44411409 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022987
protein coding gene Chr19:40511391-40607573 (-)
CAST/EiJ MGP_CASTEiJ_G0024355
protein coding gene Chr19:42388310-42496210 (-)
CBA/J MGP_CBAJ_G0024870
protein coding gene Chr19:46544388-46649191 (-)
DBA/2J MGP_DBA2J_G0025002
protein coding gene Chr19:41044935-41138138 (-)
FVB/NJ MGP_FVBNJ_G0024963
protein coding gene Chr19:40794958-40869261 (-)
LP/J MGP_LPJ_G0025088
protein coding gene Chr19:43241542-43318529 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024994
protein coding gene Chr19:46081156-46158931 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025631
protein coding gene Chr19:42608815-42685108 (-)
PWK/PhJ MGP_PWKPhJ_G0024104
protein coding gene Chr19:40938688-41034545 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023908
protein coding gene Chr19:41327186-41391408 (-)
WSB/EiJ MGP_WSBEiJ_G0024425
protein coding gene Chr19:42746170-42841440 (-)



Homology
more
  • Human Ortholog
    DNMBP, dynamin binding protein
  • Vertebrate Orthologs
    9
  • Human Ortholog
    DNMBP, dynamin binding protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ARHGEF36, TUBA
  • Links
    NCBI Gene ID: 23268
    neXtProt AC: NX_Q6XZF7
    UniProt: Q6XZF7

  • Chr Location
    10q24.2; chr10:99875571-100009953 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000025195 Ensembl Gene Model | MGI Sequence Detail 93371 C57BL/6J ±  kb
    transcript ENSMUST00000026209 Ensembl | MGI Sequence Detail 4882 Not Applicable  
    polypeptide ENSMUSP00000026209 Ensembl | MGI Sequence Detail 1580 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      6 Sequences
    • InterPro Domains
      IPR027267 AH/BAR domain superfamily
      IPR004148 BAR domain
      IPR000219 Dbl homology (DH) domain
      IPR035899 Dbl homology (DH) domain superfamily
      IPR035469 Dynamin-binding protein
      IPR035820 Dynamin-binding protein, first C-terminal SH3 domain
      IPR035817 Dynamin-binding protein, first N-terminal SH3 domain
      IPR035818 Dynamin-binding protein, second N-terminal SH3 domain
      IPR035819 Dynamin-binding protein, third N-terminal SH3 domain
      IPR001331 Guanine-nucleotide dissociation stimulator, CDC24, conserved site
      IPR001452 SH3 domain
      IPR036028 SH3-like domain superfamily
    Molecular
    Reagents
    less
    • All nucleic 17
      Genomic 2
      cDNA 14
      Primer pair 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1919222
    References
    more
    • Summaries
      All 34
      Developmental Gene Expression 3
      Gene Ontology 6
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:247397 Polle L, et al., Structural details of human tuba recruitment by InlC of Listeria monocytogenes elucidate bacterial cell-cell spreading. Structure. 2014 Feb 04;22(2):304-14

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    03/13/2019
    MGI 6.13
    The Jackson Laboratory