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Meaf6 Gene Detail
Summary
  • Symbol
    Meaf6
  • Name
    MYST/Esa1-associated factor 6
  • Synonyms
    2310005N01Rik, 2810036M01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917338
    NCBI Gene: 70088
  • Gene Overview
    MyGene.info: MEAF6
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:125085132-125110070 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 58.03 cM, cytoband D1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    43 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917338
protein coding gene Chr4:125085132-125113238 (.)
129S1/SvImJ MGP_129S1SvImJ_G0028764
protein coding gene Chr4:126670680-126702019 (+)
A/J MGP_AJ_G0028723
protein coding gene Chr4:121690219-121718925 (+)
AKR/J MGP_AKRJ_G0028676
protein coding gene Chr4:125027295-125054447 (+)
BALB/cJ MGP_BALBcJ_G0028746
protein coding gene Chr4:122279675-122307998 (+)
C3H/HeJ MGP_C3HHeJ_G0028460
protein coding gene Chr4:125107398-125135969 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029188
protein coding gene Chr4:131533500-131563673 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026461
protein coding gene Chr4:114855233-114883693 (+)
CAST/EiJ MGP_CASTEiJ_G0027893
protein coding gene Chr4:123179020-123207720 (+)
CBA/J MGP_CBAJ_G0028426
protein coding gene Chr4:134813620-134842450 (+)
DBA/2J MGP_DBA2J_G0028575
protein coding gene Chr4:122160018-122188646 (+)
FVB/NJ MGP_FVBNJ_G0028542
protein coding gene Chr4:120790066-120821803 (+)
LP/J MGP_LPJ_G0028676
protein coding gene Chr4:126953553-126983036 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028568
protein coding gene Chr4:139788675-139818287 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029226
protein coding gene Chr4:125379428-125407446 (+)
PWK/PhJ MGP_PWKPhJ_G0027614
protein coding gene Chr4:118592102-118620765 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027440
protein coding gene Chr4:121166251-121200547 (+)
WSB/EiJ MGP_WSBEiJ_G0027973
protein coding gene Chr4:125460870-125491247 (+)



Homology
more
  • Human Ortholog
    MEAF6, MYST/Esa1 associated factor 6
  • Vertebrate Orthologs
    9
  • Human Ortholog
    MEAF6, MYST/Esa1 associated factor 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C1orf149, CENP-28, EAF6, NY-SAR-91
  • Links
    NCBI Gene ID: 64769
    neXtProt AC: NX_Q9HAF1
    UniProt: Q9HAF1

  • Chr Location
    1p34.3; chr1:37489960-37514819 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 11240
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MEAF6
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
  • All Mutations and Alleles
    23
  • Chemically induced (other)
    2
  • Gene trapped
    16
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    4 involving Meaf6
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 70088 NCBI Gene Model | MGI Sequence Detail 24939 C57BL/6J ±  kb
transcript NR_151472 RefSeq | MGI Sequence Detail 4621 C57BL/6  
polypeptide Q2VPQ9 UniProt | EBI | MGI Sequence Detail 191 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR015418 Chromatin modification-related protein Eaf6
Molecular
Reagents
less
  • All nucleic 42
    cDNA 42

    Microarray probesets 3
Other
Accession IDs
less
MGI:1919914
References
more
  • Summaries
    All 38
    Gene Ontology 5
    Phenotypes 15
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory