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H1fnt Gene Detail
Summary
  • Symbol
    H1fnt
  • Name
    H1 histone family, member N, testis-specific
  • Synonyms
    1700026P10Rik, H1T2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917319
    NCBI Gene: 70069
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr15:98255986-98257293 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      1308 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 54.26 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    H1FNT, H1 histone family member N, testis specific
  • Human Ortholog
    H1FNT, H1 histone family member N, testis specific
    Orthology source: HGNC
  • Synonyms
    H1.7, H1T2
  • Links
    NCBI Gene ID: 341567
    neXtProt AC: NX_Q75WM6
    UniProt: Q75WM6

  • Chr Location
    12q13.11; chr12:48328980-48330279 (+)  GRCh38.p7

  • HCOP
    human homology predictions: H1FNT
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    12 phenotypes from 2 alleles in 2 genetic backgrounds
    22 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous null male mice display reduced fertility with asthenozoospermia, oligozoospermia, and teratozoospermia.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000048077 Ensembl Gene Model | MGI Sequence Detail 1308 C57BL/6J ±  kb
transcript ENSMUST00000060855 Ensembl | MGI Sequence Detail 1308 Not Applicable  
polypeptide ENSMUSP00000127616 Ensembl | MGI Sequence Detail 398 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    25 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 4
References
more
  • Summaries
    All 44
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 7
    Phenotypes 22
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:250931 Pan C, et al., Role of H1 linker histones in mammalian development and stem cell differentiation. Biochim Biophys Acta. 2016 Mar;1859(3):496-509

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/16/2018
MGI 6.12
The Jackson Laboratory