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Prpf4 Gene Detail
Summary
  • Symbol
    Prpf4
  • Name
    pre-mRNA processing factor 4
  • Synonyms
    1600015H11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917302
    NCBI Gene: 70052
  • Gene Overview
    MyGene.info: PRPF4
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:62408797-62426990 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 33.13 cM, cytoband C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    80 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917302
protein coding gene Chr4:62408767-62426990 (.)
129S1/SvImJ MGP_129S1SvImJ_G0028351
protein coding gene Chr4:61394410-61413009 (+)
A/J MGP_AJ_G0028312
protein coding gene Chr4:59168548-59186556 (+)
AKR/J MGP_AKRJ_G0028261
protein coding gene Chr4:60805432-60824896 (+)
BALB/cJ MGP_BALBcJ_G0028332
protein coding gene Chr4:59343784-59361977 (+)
C3H/HeJ MGP_C3HHeJ_G0028050
protein coding gene Chr4:61313975-61332424 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028772
protein coding gene Chr4:63498117-63516519 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026078
protein coding gene Chr4:56458979-56477569 (+)
CAST/EiJ MGP_CASTEiJ_G0027486
protein coding gene Chr4:59252358-59270856 (+)
CBA/J MGP_CBAJ_G0028017
protein coding gene Chr4:65692908-65711054 (+)
DBA/2J MGP_DBA2J_G0028167
protein coding gene Chr4:59026071-59044288 (+)
FVB/NJ MGP_FVBNJ_G0028132
protein coding gene Chr4:58274652-58293300 (+)
LP/J MGP_LPJ_G0028264
protein coding gene Chr4:61675439-61693589 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028159
protein coding gene Chr4:68831862-68850065 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028808
protein coding gene Chr4:60907463-60926480 (+)
PWK/PhJ MGP_PWKPhJ_G0027213
protein coding gene Chr4:57505205-57523958 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027042
protein coding gene Chr4:58356550-58376331 (+)
WSB/EiJ MGP_WSBEiJ_G0027566
protein coding gene Chr4:60893334-60911541 (+)



Homology
more
  • Human Ortholog
    PRPF4, pre-mRNA processing factor 4
  • Vertebrate Orthologs
    11
  • Human Ortholog
    PRPF4, pre-mRNA processing factor 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HPRP4, HPRP4P, PRP4, Prp4p, RP70, SNRNP60
  • Links
    NCBI Gene ID: 9128
    neXtProt AC: NX_O43172
    UniProt: O43172

  • Chr Location
    9q32; chr9:113275634-113292905 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 3446
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;2 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PRPF4
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human PRPF4 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000066148 Ensembl Gene Model | MGI Sequence Detail 18194 C57BL/6J ±  kb
transcript ENSMUST00000084524 Ensembl | MGI Sequence Detail 5223 Not Applicable  
polypeptide ENSMUSP00000081572 Ensembl | MGI Sequence Detail 521 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 74
    cDNA 74

    Microarray probesets 7
Other
Accession IDs
less
MGI:2140401, MGI:2140542
References
more
  • Summaries
    All 32
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory