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Prpf4
Gene Detail
 Symbol
Name
ID
Prpf4
PRP4 pre-mRNA processing factor 4 homolog (yeast)
MGI:1917302
Synonyms 1600015H11Rik
Feature Type protein coding gene
Genetic Map
Chromosome 4
33.13 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr4:62408797-62426990 bp, + strand
From VEGA annotation of GRCm38

  18194 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3446  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Gene Tree: Prpf4

Human
homologs
Human Homolog PRPF4, pre-mRNA processing factor 4
NCBI Gene ID 9128
neXtProt AC  NX_O43172
Human Synonyms  HPRP4, HPRP4P, PRP4, Prp4p, RP70, SNRNP60
Human Chr (Location)  9q31-q33; chr9:113275634-113293799 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human PRPF4
Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(11)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Prpf4 interacts with 314 markers (Mir1a-1, Mir1a-2, Mir10b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process mRNA processing, mRNA splicing, via spliceosome, ...
Component Cajal body, nucleus, ...
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(72)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(73) cDNA(73)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000000234 (Evidence)
Ensembl Gene ModelENSMUSG00000066148 (Evidence)
Entrez Gene70052 (Evidence)
UniGene30660
DFCITC1578476, TC1601150, TC1630761
DoTSDT.101164186, DT.40181073, DT.522403
NIA Mouse Gene IndexU004392
Consensus CDS ProjectCCDS18239.1
International Mouse Knockout Project StatusPrpf4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000234 VEGA Gene Model | MGI Sequence Detail 18194 C57BL/6J ±  kb
transcript OTTMUST00000000683 VEGA | MGI Sequence Detail 5223 Not Applicable 
polypeptide OTTMUSP00000000303 VEGA | MGI Sequence Detail 521 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(5) UniProt(4)
Polymorphisms SNPs within 2kb(80 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR020472 G-protein beta WD-40 repeat
InterPro IPR014906 Pre-mRNA processing factor 4 (PRP4)-like
InterPro IPR003648 Splicing factor motif
InterPro IPR027106 U4/U6 small nuclear ribonucleoprotein Prp4/ASTRA-associated protein 1
InterPro IPR001680 WD40 repeat
InterPro IPR019775 WD40 repeat, conserved site
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000013283 U4/U6 small nuclear ribonucleoprotein Prp4
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(36)
Other
accession IDs
MGI:2140401, MGI:2140542

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory