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Trnt1 Gene Detail
Summary
  • Symbol
    Trnt1
  • Name
    tRNA nucleotidyl transferase, CCA-adding, 1
  • Synonyms
    2410043H24Rik, 2610044E04Rik, CGI-47
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917297
    NCBI Gene: 70047
  • Gene Overview
    MyGene.info: TRNT1
Location & Maps
more
  • Sequence Map
    Chr6:106769120-106782474 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      13355 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 49.24 cM, cytoband E2
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    TRNT1, tRNA nucleotidyl transferase 1
  • Vertebrate Orthologs
    11
  • Human Ortholog
    TRNT1, tRNA nucleotidyl transferase 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CCA1, CGI-47, MtCCA, RPEM, SIFD
  • Links
    NCBI Gene ID: 51095
    neXtProt AC: NX_Q96Q11

  • Chr Location
    3p25.1; chr3:3126916-3152503 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    2 with human TRNT1 associations

Human Disease Mouse Models
       Retinitis Pigmentosa and Erythrocytic Microcytosis; RPEM   OMIM: 616959
Sideroblastic Anemia with B-Cell Immunodeficiency, Periodic Fevers, and Developmental Delay; SIFD   OMIM: 616084
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    8
  • Gene trapped
    5
  • Spontaneous
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Trnt1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023531 VEGA Gene Model | MGI Sequence Detail 13355 C57BL/6J ±  kb
transcript OTTMUST00000057363 VEGA | MGI Sequence Detail 1614 Not Applicable  
polypeptide OTTMUSP00000027662 VEGA | MGI Sequence Detail 434 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    152 from dbSNP Build 142
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000016689 CCA tRNA nucleotidyltransferase 1, mitochondrial
  • EC
  • InterPro Domains
    IPR002646 Poly A polymerase, head domain
    IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain
Molecular
Reagents
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  • All nucleic 13
    cDNA 13

    Microarray probesets 3
Other
Accession IDs
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MGI:1353629, MGI:1889337, MGI:1917240
References
more
  • Summaries
    All 33
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:151002 Pagliarini DJ, et al., A mitochondrial protein compendium elucidates complex I disease biology. Cell. 2008 Jul 11;134(1):112-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory