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Cep85 Gene Detail
Summary
  • Symbol
    Cep85
  • Name
    centrosomal protein 85
  • Synonyms
    2410030J07Rik, Ccdc21
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917262
    NCBI Gene: 70012
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:133857169-133914420 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 66.50 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1708 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917262
 protein coding gene Chr4:133857169-133914423 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028914
 protein coding gene Chr4:136464227-136519225 (-)
A/J MGP_AJ_G0028873
 protein coding gene Chr4:130717740-130776138 (-)
AKR/J MGP_AKRJ_G0028825
 protein coding gene Chr4:134467871-134519700 (-)
BALB/cJ MGP_BALBcJ_G0028896
 protein coding gene Chr4:131367972-131422079 (-)
C3H/HeJ MGP_C3HHeJ_G0028610
 protein coding gene Chr4:134704825-134765268 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029338
 protein coding gene Chr4:141370232-141453667 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026609
 protein coding gene Chr4:123784180-123836956 (-)
CAST/EiJ MGP_CASTEiJ_G0028043
 protein coding gene Chr4:132824379-132882191 (-)
CBA/J MGP_CBAJ_G0028575
 protein coding gene Chr4:145090917-145151397 (-)
DBA/2J MGP_DBA2J_G0028724
 protein coding gene Chr4:131150954-131207726 (-)
FVB/NJ MGP_FVBNJ_G0028692
 protein coding gene Chr4:130043421-130098023 (-)
LP/J MGP_LPJ_G0028825
 protein coding gene Chr4:136548153-136597708 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028717
 protein coding gene Chr4:149585303-149660313 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029376
 protein coding gene Chr4:134888495-134944495 (-)
PWK/PhJ MGP_PWKPhJ_G0027763
 protein coding gene Chr4:127877513-127931651 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027589
 protein coding gene Chr4:130733899-130789107 (-)
WSB/EiJ MGP_WSBEiJ_G0028122
 protein coding gene Chr4:135077077-135129479 (-)



Homology
more
  • Human Ortholog
    CEP85, centrosomal protein 85
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CEP85, centrosomal protein 85
  • Synonyms
    CCDC21
  • Links
    NCBI Gene ID: 64793
    UniProt: Q6P2H3

  • Chr Location
    1p36.11; chr1:26234200-26278808 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    135
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    1
  • Gene trapped
    130
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    4 involving Cep85
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    259 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    48
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    57
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 70012 NCBI Gene Model | MGI Sequence Detail 57252 C57BL/6J ±  kb
transcript NM_144527 RefSeq | MGI Sequence Detail 3878 C57BL/6  
polypeptide Q8BMK0 UniProt | EBI | MGI Sequence Detail 761 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 57
    cDNA 57

    Microarray probesets 4
Other
Accession IDs
less
MGI:2140202, MGI:2140203
References
more
  • Summaries
    All 39
    Gene Ontology 6
    Phenotypes 12
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory