Cep85 Gene Detail

Summary

• Symbol
  Cep85
• Name
  centrosomal protein 85
• Synonyms
  2410030J07Rik, Ccdc21

• Feature Type
  protein coding gene
• IDs
  MGI:1917262
  NCBI Gene: 70012
• Alliance
  gene page

Location & Maps

• Sequence Map
  Chr4:134129858-134187112 bp, - strand
• From VEGA annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    57255 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 4, 66.50 cM
• Mapping Data
  2 experiments

Homology

• Human Ortholog
  CEP85, centrosomal protein 85

• Vertebrate Orthologs
  9

• Human Ortholog
  CEP85, centrosomal protein 85
  Orthology source: HomoloGene, HGNC
• Synonyms
  CCDC21
• Links
  HGNC:25309

  NCBI Gene ID: 64793

  neXtProt AC: NX_Q6P2H3

  UniProt: Q6P2H3

  
  
• Chr Location
  1p36.11; chr1:26234153-26278810 (+)  GRCh38.p7

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• HomoloGene
  Vertebrate Homology Class 11254
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 macaque, rhesus
  
• HCOP
  human homology predictions: CEP85
• Gene Tree
  Cep85
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  11 phenotype references
  

• All Mutations and Alleles
  135
• Chemically induced (other)
  2
• Gene trapped
  131
• Radiation induced
  1
• Targeted
  1
• Genomic Mutations
  4 involving Cep85
• Incidental Mutations
  APF , CvDC
• Find Mice (IMSR)
  245 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  15
• GO References
  3

• External Resources
  FuncBase

Expression

• cDNA Data
  56

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  GEISHA CEP85
  Xenbase cep85

Interactions

• Cep85 interacts with 227 markers (Mir1a-1, Mir1a-2, Mir7-1, ...) View All

Sequences &
Gene Models

• All Sequences
  56
• RefSeq
  8
• UniProt
  4
• CCDS
  CCDS18765.1
• UniGene
  26542

• VEGA
  OTTMUSG00000010361 (Evidence)
• Ensembl
  ENSMUSG00000037443 (Evidence)
• NCBI Gene
  70012

Representative Sequences			Length	Strain/Species
genomic	OTTMUSG00000010361	VEGA Gene Model | MGI Sequence Detail	57255	C57BL/6J
transcript	OTTMUST00000024150	VEGA | MGI Sequence Detail	3893	Not Applicable
polypeptide	OTTMUSP00000011105	VEGA | MGI Sequence Detail	761	Not Applicable

Polymorphisms

• SNPs within 2kb
  432 from dbSNP Build 142

Protein
Information

• UniProt
  4 Sequences
• Protein Ontology
  PR:000029352 centrosomal protein of 85 kDa
  (term hierarchy)
• InterPro Domains
  IPR029777 Centrosomal protein of 85kDa

Molecular
Reagents

• All nucleic 56

  cDNA 56

  
  

  Microarray probesets 4

Other
Accession IDs

MGI:2140202, MGI:2140203

References

• Summaries
  All 35

  Gene Ontology 3

  Phenotypes 11
• Earliest
  J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
• Latest
  J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9