About   Help   FAQ
Chn2 Gene Detail
Summary
  • Symbol
    Chn2
  • Name
    chimerin 2
  • Synonyms
    1700026N20Rik, 4930557O16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917243
    NCBI Gene: 69993
  • Gene Overview
    MyGene.info: CHN2
Location & Maps
more
  • Sequence Map
    Chr6:54039554-54301810 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      262257 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 26.54 cM, cytoband B3
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CHN2, chimerin 2
  • Vertebrate Orthologs
    8
  • Human Ortholog
    CHN2, chimerin 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ARHGAP3, BCH, CHN2-3, RHOGAP3
  • Links
    NCBI Gene ID: 1124
    neXtProt AC: NX_P52757

  • Chr Location
    7p15.3; chr7:29146547-29514335 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    35
  • Gene trapped
    33
  • Targeted
    2
  • Incidental Mutations
Mice homozygous for a targeted allele exhibit impaired infrapyramidal tract neuron prunning.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023143 VEGA Gene Model | MGI Sequence Detail 262257 C57BL/6J ±  kb
transcript OTTMUST00000055937 VEGA | MGI Sequence Detail 2418 Not Applicable  
polypeptide OTTMUSP00000026841 VEGA | MGI Sequence Detail 468 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    2311 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 7
Other
Accession IDs
less
MGI:1922054
References
more
  • Summaries
    All 34
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:186252 Riccomagno MM, et al., The RacGAP beta2-Chimaerin Selectively Mediates Axonal Pruning in the Hippocampus. Cell. 2012 Jun 22;149(7):1594-606

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/19/2016
MGI 6.04
The Jackson Laboratory