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Mettl18 Gene Detail
Summary
  • Symbol
    Mettl18
  • Name
    methyltransferase like 18
  • Synonyms
    2810422O20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917212
    NCBI Gene: 69962
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:163994891-163997243 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 71.30 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    45 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917212
protein coding gene Chr1:163994889-163997243 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016676
protein coding gene Chr1:169399498-169403973 (+)
A/J MGP_AJ_G0016657
protein coding gene Chr1:162502297-162504676 (+)
AKR/J MGP_AKRJ_G0016623
protein coding gene Chr1:167431706-167434033 (+)
BALB/cJ MGP_BALBcJ_G0016618
protein coding gene Chr1:163004370-163007058 (+)
C3H/HeJ MGP_C3HHeJ_G0016442
protein coding gene Chr1:167616984-167619309 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017079
protein coding gene Chr1:175105644-175107940 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014788
protein coding gene Chr1:154478799-154480954 (+)
CAST/EiJ MGP_CASTEiJ_G0016022
protein coding gene Chr1:167247068-167249375 (+)
CBA/J MGP_CBAJ_G0016417
protein coding gene Chr1:181332647-181334961 (+)
DBA/2J MGP_DBA2J_G0016523
protein coding gene Chr1:161404892-161407224 (+)
FVB/NJ MGP_FVBNJ_G0016521
protein coding gene Chr1:159850300-159852598 (+)
LP/J MGP_LPJ_G0016594
protein coding gene Chr1:170487148-170489991 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016546
protein coding gene Chr1:188849605-188852441 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017115
protein coding gene Chr1:167258167-167260520 (+)
PWK/PhJ MGP_PWKPhJ_G0015808
protein coding gene Chr1:160593814-160596151 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015595
protein coding gene Chr1:166136763-166139762 (+)
WSB/EiJ MGP_WSBEiJ_G0016084
protein coding gene Chr1:167426057-167428389 (+)



Homology
more
  • Human Ortholog
    METTL18, methyltransferase like 18
  • Vertebrate Orthologs
    10
  • Human Ortholog
    METTL18, methyltransferase like 18
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AsTP2, C1orf156, HPM1
  • Links
    NCBI Gene ID: 92342
    neXtProt AC: NX_O95568
    UniProt: O95568

  • Chr Location
    1q24.2; chr1:169792524-169794976 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    2
  • Gene trapped
    7
  • Targeted
    1
  • Genomic Mutations
    2 involving Mettl18
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69962 NCBI Gene Model | MGI Sequence Detail 2353 C57BL/6J ±  kb
transcript NM_027279 RefSeq | MGI Sequence Detail 1531 C57BL/6  
polypeptide Q9CZ09 UniProt | EBI | MGI Sequence Detail 362 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 20

    Microarray probesets 3
Other
Accession IDs
less
MGI:2138673
References
more
  • Summaries
    All 28
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory