About   Help   FAQ
Fars2
Gene Detail
 Symbol
Name
ID
Fars2
phenylalanine-tRNA synthetase 2 (mitochondrial)
MGI:1917205
Synonyms 2810431B21Rik, 6720478K01Rik, Fars1
Feature Type protein coding gene
Genetic Map
Chromosome 13
14.44 cM, cytoband A5
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr13:36117411-36537592 bp, + strand
From Ensembl annotation of GRCm38

  420182 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4788  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Fars2

Human
homologs
Human Homolog FARS2, phenylalanyl-tRNA synthetase 2, mitochondrial
NCBI Gene ID 10667
neXtProt AC  NX_O95363
Human Synonyms  COXPD14, dJ520B18.2, FARS1, HSPC320, PheRS
Human Chr (Location)  6p25.1; chr6:5261018-5771583 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human FARS2
Alleles
and
phenotypes
All alleles(32) : Gene trapped(30) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process phenylalanyl-tRNA aminoacylation, translation, ...
Component cytoplasm, mitochondrion
Function aminoacyl-tRNA ligase activity, ATP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Images (12)
Theiler Stages: 22
Assay TypeResults
RNA in situ 94
cDNA source data(59)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(59) cDNA(59)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000021420 (Evidence)
Entrez Gene69955 (Evidence)
UniGene70690
DFCITC1577454, TC1595661, TC1627803, TC1681643
NIA Mouse Gene IndexU014728, U148575
EC6.1.1.20
Consensus CDS ProjectCCDS26453.1, CCDS26454.1
International Mouse Knockout Project StatusFars2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021420 Ensembl Gene Model | MGI Sequence Detail 420182 C57BL/6J ±  kb
transcript ENSMUST00000021857 Ensembl | MGI Sequence Detail 2125 Not Applicable 
polypeptide ENSMUSP00000021857 Ensembl | MGI Sequence Detail 451 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(12) UniProt(3)
Polymorphisms SNPs within 2kb(3103 from dbSNP Build 137)    SNPs within 2kb including multiple locations(3109)
Protein-related
information
ResourceIDDescription
InterPro IPR006195 Aminoacyl-tRNA synthetase, class II
InterPro IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding
InterPro IPR002319 Phenylalanyl-tRNA synthetase
InterPro IPR004530 Phenylalanyl-tRNA synthetase, class IIc, mitochondrial
Protein Ontology PR:000007345 phenylalanine--tRNA ligase, mitochondrial
References (Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:151002 Pagliarini DJ, et al., A mitochondrial protein compendium elucidates complex I disease biology. Cell. 2008 Jul 11;134(1):112-23
All references(33)
Other
accession IDs
MGI:1925151

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/15/2014
MGI 5.18
The Jackson Laboratory