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Rcbtb2 Gene Detail
Summary
  • Symbol
    Rcbtb2
  • Name
    regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
  • Synonyms
    2610028E02Rik, 2810420M18Rik, Chc1l, Rc/btb2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917200
    NCBI Gene: 105670
  • Gene Overview
    MyGene.info: RCBTB2
Location & Maps
more
  • Sequence Map
    Chr14:73123037-73207843 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      84807 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 38.66 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    RCBTB2, RCC1 and BTB domain containing protein 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RCBTB2, RCC1 and BTB domain containing protein 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CHC1L, RLG
  • Links
    NCBI Gene ID: 1102
    neXtProt AC: NX_O95199

  • Chr Location
    13q14.3; chr13:48488963-48533256 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 970
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: RCBTB2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    19
  • Chemically induced (other)
    1
  • Gene trapped
    18
  • Genomic Mutations
    1 involving Rcbtb2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036135 VEGA Gene Model | MGI Sequence Detail 84807 C57BL/6J ±  kb
transcript OTTMUST00000092884 VEGA | MGI Sequence Detail 3531 Not Applicable  
polypeptide OTTMUSP00000051429 VEGA | MGI Sequence Detail 551 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    621 from dbSNP Build 142
Protein
Information
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  • UniProt
    15 Sequences
  • Protein Ontology
    PR:000030818 RCC1 and BTB domain-containing protein 2
  • InterPro Domains
    IPR000210 BTB/POZ domain
    IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
    IPR000408 Regulator of chromosome condensation, RCC1
    IPR011333 SKP1/BTB/POZ domain
Molecular
Reagents
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  • All nucleic 14
    cDNA 14

    Microarray probesets 6
Other
Accession IDs
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MGI:1919062, MGI:2145647, MGI:2145809
References
more
  • Summaries
    All 24
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:187907 Wang J, et al., Mouse RC/BTB2, a member of the RCC1 superfamily, localizes to spermatid acrosomal vesicles. PLoS One. 2012;7(6):e39846

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory