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Rcbtb2 Gene Detail
Summary
  • Symbol
    Rcbtb2
  • Name
    regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
  • Synonyms
    2610028E02Rik, 2810420M18Rik, Chc1l, Rc/btb2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917200
    NCBI Gene: 105670
  • Gene Overview
    MyGene.info: RCBTB2
  • Alliance
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:73138773-73184055 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 38.66 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    376 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917200
protein coding gene Chr14:73123037-73207843 (.)
129S1/SvImJ MGP_129S1SvImJ_G0021554
protein coding gene Chr14:67881757-67944712 (+)
A/J MGP_AJ_G0021513
protein coding gene Chr14:66393327-66456096 (+)
AKR/J MGP_AKRJ_G0021489
protein coding gene Chr14:68348335-68411779 (+)
BALB/cJ MGP_BALBcJ_G0021519
protein coding gene Chr14:66156504-66223174 (+)
C3H/HeJ MGP_C3HHeJ_G0021296
protein coding gene Chr14:68069149-68131484 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021960
protein coding gene Chr14:70866442-70935656 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019498
protein coding gene Chr14:64083978-64180149 (+)
CAST/EiJ MGP_CASTEiJ_G0020814
protein coding gene Chr14:64732095-64796644 (+)
CBA/J MGP_CBAJ_G0021264
protein coding gene Chr14:73096655-73162243 (+)
DBA/2J MGP_DBA2J_G0021387
protein coding gene Chr14:65776681-65838679 (+)
FVB/NJ MGP_FVBNJ_G0021365
protein coding gene Chr14:65159634-65223033 (+)
LP/J MGP_LPJ_G0021457
protein coding gene Chr14:69052971-69114577 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021394
protein coding gene Chr14:71933061-71994769 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021982
protein coding gene Chr14:67615511-67680698 (+)
PWK/PhJ MGP_PWKPhJ_G0020557
protein coding gene Chr14:62548723-62612168 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020392
protein coding gene Chr14:63573819-63650505 (+)
WSB/EiJ MGP_WSBEiJ_G0020867
protein coding gene Chr14:67971945-68034334 (+)



Homology
more
  • Human Ortholog
    RCBTB2, RCC1 and BTB domain containing protein 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RCBTB2, RCC1 and BTB domain containing protein 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CHC1L, RLG
  • Links
    NCBI Gene ID: 1102
    neXtProt AC: NX_O95199
    UniProt: O95199

  • Chr Location
    13q14.2; chr13:48488963-48535995 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 970
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: RCBTB2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 105670 NCBI Gene Model | MGI Sequence Detail 45283 C57BL/6J ±  kb
transcript NR_033185 RefSeq | MGI Sequence Detail 3773 C57BL/6  
polypeptide Q99LJ7 UniProt | EBI | MGI Sequence Detail 551 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    14 Sequences
  • InterPro Domains
    IPR000210 BTB/POZ domain
    IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
    IPR000408 Regulator of chromosome condensation, RCC1
    IPR011333 SKP1/BTB/POZ domain superfamily
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 6
Other
Accession IDs
less
MGI:1919062, MGI:2145647, MGI:2145809
References
more
  • Summaries
    All 26
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:187907 Wang J, et al., Mouse RC/BTB2, a member of the RCC1 superfamily, localizes to spermatid acrosomal vesicles. PLoS One. 2012;7(6):e39846

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory