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Lrch4 Gene Detail
Summary
  • Symbol
    Lrch4
  • Name
    leucine-rich repeats and calponin homology (CH) domain containing 4
  • Synonyms
    2810008P14Rik, 2900069C24Rik, LRN, LRRN4, SAP25
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917193
    NCBI Gene: 231798
  • Gene Overview
    MyGene.info: LRCH4
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:137629123-137641099 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 76.59 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    56 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917193
protein coding gene Chr5:137629121-137641099 (.)
129S1/SvImJ MGP_129S1SvImJ_G0030236
protein coding gene Chr5:142406283-142418232 (+)
A/J MGP_AJ_G0030204
protein coding gene Chr5:136194316-136206761 (+)
AKR/J MGP_AKRJ_G0030137
protein coding gene Chr5:140623734-140635512 (+)
BALB/cJ MGP_BALBcJ_G0030214
protein coding gene Chr5:137562494-137581230 (+)
C3H/HeJ MGP_C3HHeJ_G0029930
protein coding gene Chr5:141276213-141288187 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030666
protein coding gene Chr5:147665724-147679204 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027884
protein coding gene Chr5:130437637-130449600 (+)
CAST/EiJ MGP_CASTEiJ_G0029340
protein coding gene Chr5:140677422-140689380 (+)
CBA/J MGP_CBAJ_G0029900
protein coding gene Chr5:153537979-153553185 (+)
DBA/2J MGP_DBA2J_G0030051
protein coding gene Chr5:136096020-136108003 (+)
FVB/NJ MGP_FVBNJ_G0030006
protein coding gene Chr5:135303595-135315669 (+)
LP/J MGP_LPJ_G0030140
protein coding gene Chr5:142878477-142890450 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030038
protein coding gene Chr5:156356774-156368743 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030707
protein coding gene Chr5:140474516-140486377 (+)
PWK/PhJ MGP_PWKPhJ_G0029053
protein coding gene Chr5:135186629-135198767 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028889
protein coding gene Chr5:138038546-138055267 (+)
WSB/EiJ MGP_WSBEiJ_G0029413
protein coding gene Chr5:141205565-141217346 (+)



Homology
more
  • Human Ortholog
    LRCH4, leucine rich repeats and calponin homology domain containing 4
  • Vertebrate Orthologs
    8
  • Human Ortholog
    LRCH4, leucine rich repeats and calponin homology domain containing 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LRN, LRRN1, LRRN4, PP14183
  • Links
    NCBI Gene ID: 4034
    neXtProt AC: NX_O75427
    UniProt: O75427

  • Chr Location
    7q22.1; chr7:100574011-100586188 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 231798 NCBI Gene Model | MGI Sequence Detail 11977 C57BL/6J ±  kb
transcript NM_146164 RefSeq | MGI Sequence Detail 3081 C57BL/6  
polypeptide NP_666276 RefSeq | MGI Sequence Detail 680 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    Genomic 1
    cDNA 16

    Microarray probesets 8
Other
Accession IDs
less
MGI:1924227, MGI:2140932
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 1
  • Earliest
    J:6660 Rougeon F, et al., Molecular cloning of a mouse submaxillary gland renin cDNA fragment. Proc Natl Acad Sci U S A. 1981 Oct;78(10):6367-71
  • Latest
    J:162220 Magdaleno S, et al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory