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Tspan18 Gene Detail
Summary
  • Symbol
    Tspan18
  • Name
    tetraspanin 18
  • Synonyms
    2610042G18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917186
    NCBI Gene: 241556
  • Gene Overview
    MyGene.info: TSPAN18
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:93201760-93334505 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 51.37 cM, cytoband E1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1039 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917186
protein coding gene Chr2:93201760-93334553 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026174
protein coding gene Chr2:94693368-94825445 (-)
A/J MGP_AJ_G0026135
protein coding gene Chr2:90844557-90973382 (-)
AKR/J MGP_AKRJ_G0026116
protein coding gene Chr2:93382262-93519821 (-)
BALB/cJ MGP_BALBcJ_G0026144
protein coding gene Chr2:91035295-91168709 (-)
C3H/HeJ MGP_C3HHeJ_G0025895
protein coding gene Chr2:93659599-93794463 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026595
protein coding gene Chr2:97916706-98058969 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023986
protein coding gene Chr2:87330511-87464143 (-)
CAST/EiJ MGP_CASTEiJ_G0025360
protein coding gene Chr2:94241653-94382296 (-)
CBA/J MGP_CBAJ_G0025873
protein coding gene Chr2:101319738-101465773 (-)
DBA/2J MGP_DBA2J_G0026009
protein coding gene Chr2:90453800-90585076 (-)
FVB/NJ MGP_FVBNJ_G0025972
protein coding gene Chr2:89565868-89699644 (-)
LP/J MGP_LPJ_G0026113
protein coding gene Chr2:94893612-95036473 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025998
protein coding gene Chr2:104257643-104398527 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026649
protein coding gene Chr2:93460462-93599677 (-)
PWK/PhJ MGP_PWKPhJ_G0025095
protein coding gene Chr2:90196045-90329171 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024896
protein coding gene Chr2:93031933-93164708 (-)
WSB/EiJ MGP_WSBEiJ_G0025427
protein coding gene Chr2:94077045-94209478 (-)



Homology
more
  • Human Ortholog
    TSPAN18, tetraspanin 18
  • Vertebrate Orthologs
    11
  • Human Ortholog
    TSPAN18, tetraspanin 18
    Orthology source: HomoloGene, HGNC
  • Synonyms
    TSPAN
  • Links
    NCBI Gene ID: 90139
    neXtProt AC: NX_Q96SJ8
    UniProt: Q96SJ8

  • Chr Location
    11p11.2; chr11:44727148-44932427 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    5
  • Genomic Mutations
    4 involving Tspan18
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027217 Ensembl Gene Model | MGI Sequence Detail 132746 C57BL/6J ±  kb
transcript ENSMUST00000111265 Ensembl | MGI Sequence Detail 3751 Not Applicable  
polypeptide ENSMUSP00000106896 Ensembl | MGI Sequence Detail 248 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    Genomic 1
    cDNA 10

    Microarray probesets 5
Other
Accession IDs
less
MGI:3035432
References
more
  • Summaries
    All 41
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 12
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:246066 Sundberg JP, et al., Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program. PLoS One. 2017;12(7):e0180682

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory