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Agk
Gene Detail
Symbol

Name
ID
Agk
acylglycerol kinase
MGI:1917173
Synonyms
2610037M15Rik, MuLK
Feature Type
protein coding gene
Genetic Map
Chromosome 6
18.82 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr6:40325478-40396762 bp, + strand
From Ensembl annotation of GRCm38

  71285 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41239  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: AGK
Protein SuperFamily: multi-substrate lipid kinase
Gene Tree: Agk

Human
homologs
AGK, acylglycerol kinase
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 55750
neXtProt AC: NX_Q53H12

Human Synonyms: CATC5, CTRCT38, MTDPS10, MULK

Human Chr (Location): 7q34; chr7:141551278-141654409 (+)  GRCh38.p2

Disease Associations: (2) Diseases Associated with Human AGK

Mutations,
alleles, and
phenotypes
All mutations/alleles(59) : Gene trapped(57) Targeted(2)
Incidental mutations (data from Mutagenetix , CvDC )
Interactions
Agk interacts with 124 markers (Mir1b, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process ceramide biosynthetic process, lipid phosphorylation, ...
Component intracellular membrane-bounded organelle, membrane, ...
Function acylglycerol kinase activity, ATP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (106)    Tissues (98)    Images (20)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 106
cDNA source data(47)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase agk ; ZFIN agk    NEW 
Molecular
reagents
All nucleic(47) cDNA(47)
Microarray probesets(5)
Other database
links
Ensembl Gene Model ENSMUSG00000029916 (Evidence)
Entrez Gene 69923 (Evidence)
UniGene 32840
DFCI TC1593740, TC1591626, TC1578775, TC1689217, TC1620629, TC1616705
DoTS DT.99847081, DT.99847241, DT.91307259, DT.101718079, DT.101188603, DT.55248422, DT.480967
NIA Mouse Gene Index U042731, U044602
EC 2.7.1.94, 2.7.1.107
Consensus CDS Project CCDS20027.1
International Mouse Phenotyping Consortium Status Agk
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029916 Ensembl Gene Model | MGI Sequence Detail 71285 C57BL/6J ±  kb
transcript ENSMUST00000031977 Ensembl | MGI Sequence Detail 2225 Not Applicable 
polypeptide ENSMUSP00000031977 Ensembl | MGI Sequence Detail 421 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(6) UniProt(1)
Polymorphisms
SNPs within 2kb(238 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016064 ATP-NAD kinase-like domain
InterPro IPR001206 Diacylglycerol kinase, catalytic domain
Protein Ontology PR:000003831 acylglycerol kinase, mitochondrial
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(38)
Other
accession IDs
MGI:1889847

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory