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Rab3b
Gene Detail
Symbol

Name
ID
Rab3b
RAB3B, member RAS oncogene family
MGI:1917158
Feature Type
protein coding gene
Genetic Map
Chromosome 4
50.67 cM, cytoband C7
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:108879063-108943324 bp, + strand
From VEGA annotation of GRCm38

  64262 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2149  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: RAB3B
Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab3b

Human
homologs
RAB3B, RAB3B, member RAS oncogene family
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 5865
neXtProt AC: NX_P20337

Human Chr (Location): 1p32-p31; chr1:51907956-51990764 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(7) Targeted(2)
Genomic Mutations involving Rab3b (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele are viable with no apparent decrease in weight or fertility.
 
Interactions
Rab3b interacts with 282 markers (Mir7-2, Mir7b, Mir10b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (34 annotations)
Process antigen processing and presentation, intracellular protein transport, ...
Component cytoplasm, cytosol, ...
Function GDP binding, GTPase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (1)    Tissues (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 1
cDNA source data(20)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase rab3b    NEW 
Molecular
reagents
All nucleic(21) cDNA(20) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000008236 (Evidence)
Ensembl Gene Model ENSMUSG00000003411 (Evidence)
Entrez Gene 69908 (Evidence)
UniGene 41580
DFCI TC1581170
DoTS DT.528937
NIA Mouse Gene Index U004632
Consensus CDS Project CCDS18459.1
International Mouse Phenotyping Consortium Status Rab3b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008236 VEGA Gene Model | MGI Sequence Detail 64262 C57BL/6J ±  kb
transcript OTTMUST00000018723 VEGA | MGI Sequence Detail 1078 Not Applicable 
polypeptide OTTMUSP00000008596 VEGA | MGI Sequence Detail 228 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(487 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003579 Small GTPase superfamily, Rab type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013618 ras-related protein Rab-3B
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(43)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory