About   Help   FAQ
Rab3b
Gene Detail
 Symbol
Name
ID
Rab3b
RAB3B, member RAS oncogene family
MGI:1917158
Feature Type protein coding gene
Genetic Map
Chromosome 4
50.67 cM, cytoband C7
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:108879063-108943324 bp, + strand
From VEGA annotation of GRCm38

  64262 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2149  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab3b

Human
homologs
Human Homolog RAB3B, RAB3B, member RAS oncogene family
NCBI Gene ID 5865
neXtProt AC  NX_P20337
Human Chr (Location)  1p32-p31; chr1:51907956-51990764 (-)  GRCh38
Alleles
and
phenotypes
All alleles(8) : Gene trapped(7) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele are viable with no apparent decrease in weight or fertility.
 
Gene Ontology
(GO)
classifications
All GO classifications: (24 annotations)
Process antigen processing and presentation, peptidyl-cysteine methylation, ...
Component cytoplasm, cytosol, ...
Function GDP binding, GTP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (1)    Tissues (1)   
Theiler Stages: 24
Assay TypeResults
RT-PCR 1
cDNA source data(20)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress
Molecular
reagents
All nucleic(21) cDNA(20) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000008236 (Evidence)
Ensembl Gene ModelENSMUSG00000003411 (Evidence)
Entrez Gene69908 (Evidence)
UniGene41580
DFCITC1581170
DoTSDT.528937
NIA Mouse Gene IndexU004632
Consensus CDS ProjectCCDS18459.1
International Mouse Knockout Project StatusRab3b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008236 VEGA Gene Model | MGI Sequence Detail 64262 C57BL/6J ±  kb
transcript OTTMUST00000018723 VEGA | MGI Sequence Detail 1078 Not Applicable 
polypeptide OTTMUSP00000008596 VEGA | MGI Sequence Detail 228 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(487 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003579 Small GTPase superfamily, Rab type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013618 ras-related protein Rab-3B
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(44)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/15/2014
MGI 5.18
The Jackson Laboratory