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Mfsd11 Gene Detail
Summary
  • Symbol
    Mfsd11
  • Name
    major facilitator superfamily domain containing 11
  • Synonyms
    2600014M03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917150
    NCBI Gene: 69900
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:116743266-116766461 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 81.49 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    665 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917150
 protein coding gene Chr11:116743037-116766486 (+)
129S1/SvImJ no annotation
A/J ENSMUSG00195027254
 protein coding gene Chr11:113768081-113800453 (+)
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ ENSMUSG00175038755
 protein coding gene Chr11:114019813-114052183 (+)
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0017458
 protein coding gene Chr11:112690389-112713136 (+)
CAST/EiJ ENSTCUG00005028170
 protein coding gene Chr11:113443639-113475580 (+)
CBA/J no annotation
DBA/2J no annotation
FVB/NJ ENSMUSG00205018750
 protein coding gene Chr11:113897831-113929983 (+)
JF1/MsJ ENSUMUG00000051801
 protein coding gene Chr11:114340093-114372383 (+)
LP/J ENSMUSG00230045221
 protein coding gene Chr11:115113024-115145395 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ ENSLUMG00010020492
 protein coding gene Chr11:113844849-113877130 (+)
SPRET/EiJ ENSMSPG00010040198
 protein coding gene Chr11:114408407-114439733 (+)
WSB/EiJ ENSIUOG00005041019
 protein coding gene Chr11:113851875-113884248 (+)



Homology
more
  • Human Ortholog
    MFSD11, major facilitator superfamily domain containing 11
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MFSD11, major facilitator superfamily domain containing 11
  • Synonyms
    ET
  • Links
    NCBI Gene ID: 79157
    UniProt: O43934

  • Chr Location
    17q25.1-q25.2; chr17:76735865-76803805 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    655
  • Tissues
    25
  • cDNA Data
    54
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020818 Ensembl Gene Model | MGI Sequence Detail 23196 C57BL/6J ±  kb
transcript ENSMUST00000021173 Ensembl | MGI Sequence Detail 3298 Not Applicable  
polypeptide ENSMUSP00000021173 Ensembl | MGI Sequence Detail 449 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 55
    cDNA 54
    Primer pair 1
    Antibodies 2

    Microarray probesets 5
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:44430 Sureau A, et al., Characterization of multiple alternative RNAs resulting from antisense transcription of the PR264/SC35 splicing factor gene. Nucleic Acids Res. 1997 Nov 15;25(22):4513-22
  • Latest
    J:249222 Perland E, et al., The Putative SLC Transporters Mfsd5 and Mfsd11 Are Abundantly Expressed in the Mouse Brain and Have a Potential Role in Energy Homeostasis. PLoS One. 2016;11(6):e0156912
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory