Nt5m
Gene Detail

Symbol Name ID

Nt5m 5',3'-nucleotidase, mitochondrial MGI:1917127

Synonyms

2010013E09Rik, dNT-2

Feature Type

protein coding gene

Genetic Map

Chromosome 11

37.80 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr11:59839447-59880968 bp, + strand From VEGA annotation of GRCm38   41522 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:10622  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: 5',3'-deoxyribonucleotidase, NT5M type
Gene Tree: Nt5m

Human homologs

Human Homolog		NT5M, 5',3'-nucleotidase, mitochondrial
NCBI Gene ID		56953
neXtProt AC		NX_Q9NPB1
Human Synonyms		dNT2, dNT-2, mdN
Human Chr (Location)		17p11.2; chr17:17206680-17250977 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(43) : Targeted(4) Gene trapped(39)

Gene Ontology (GO) classifications

All GO classifications: (11 annotations)

Process	dephosphorylation, dUMP catabolic process, ...
Component	mitochondrion
Function	5'-nucleotidase activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (123)    Tissues (98)    Images (25)
Theiler Stages: 22, 23

Assay Type	Results
RNA in situ	123

cDNA source data(49)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(50) Genomic(1) cDNA(49)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000008096 (Evidence)
Ensembl Gene Model	ENSMUSG00000032615 (Evidence)
Entrez Gene	103850 (Evidence)
UniGene	41761
DFCI	TC1581676, TC1600721, TC1604179, TC1614608
DoTS	DT.101376080, DT.40174663, DT.533811, DT.91333729, DT.97395138
NIA Mouse Gene Index	U012689, U124799
EC	3.1.3.-
Consensus CDS Project	CCDS24779.1
International Mouse Knockout Project Status	Nt5m

Sequences

Length	Strain/Species
genomic	OTTMUSG00000008096	VEGA Gene Model | MGI Sequence Detail	41522	C57BL/6J
transcript	OTTMUST00000018408	VEGA | MGI Sequence Detail	1306	Not Applicable
polypeptide	OTTMUSP00000008461	VEGA | MGI Sequence Detail	220	Not Applicable

All sequences(36) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(60 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR010708	5'(3')-deoxyribonucleotidase
InterPro	IPR023214	HAD-like domain
Protein Ontology	PR:000011457	5'(3')-deoxyribonucleotidase, mitochondrial

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)

Other accession IDs

MGI:2144290