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Ttc39b Gene Detail
Summary
  • Symbol
    Ttc39b
  • Name
    tetratricopeptide repeat domain 39B
  • Synonyms
    1810054D07Rik, 9130422G05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917113
    NCBI Gene: 69863
  • Alliance
    genome feature page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:83138537-83242488 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 39.41 cM, cytoband C3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2933 from dbSNP Build 142
  • Strain Annotations
    27
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917113
 protein coding gene Chr4:83138537-83242492 (-)
129S1/SvImJ ENSMUSG00200000656
 protein coding gene Chr4:78064489-78167074 (-)
129S1/SvImJ ENSMUSG00200000650
 protein coding gene Chr4:78061741-78065493 (-)
A/J ENSMUSG00195005867
 protein coding gene Chr4:78639923-78751379 (-)
AKR/J ENSMUSG00220007699
 protein coding gene Chr4:78066969-78070770 (-)
AKR/J ENSMUSG00220007702
 protein coding gene Chr4:78069778-78172385 (-)
BALB/cJ ENSMUSG00180008155
 protein coding gene Chr4:77599902-77711341 (-)
C3H/HeJ ENSMUSG00175004079
 protein coding gene Chr4:78547200-78649785 (-)
C3H/HeJ ENSMUSG00175004074
 protein coding gene Chr4:78544391-78548192 (-)
C57BL/6NJ ENSMUSG00215002097
 protein coding gene Chr4:78501377-78505178 (-)
C57BL/6NJ ENSMUSG00215002101
 protein coding gene Chr4:78504186-78606794 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026122
 protein coding gene Chr4:75879542-75983754 (-)
CAST/EiJ ENSTCUG00005000793
 protein coding gene Chr4:77990446-78094392 (-)
CBA/J ENSMUSG00210000816
 protein coding gene Chr4:78137937-78141738 (-)
CBA/J ENSMUSG00210000822
 protein coding gene Chr4:78140746-78243339 (-)
DBA/2J ENSMUSG00185000728
 protein coding gene Chr4:78717716-78829137 (-)
FVB/NJ ENSMUSG00205001369
 protein coding gene Chr4:77011522-77015326 (-)
FVB/NJ ENSMUSG00205001372
 protein coding gene Chr4:77014334-77116934 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230016622
 protein coding gene Chr4:82143225-82147051 (-)
LP/J ENSMUSG00230016648
 protein coding gene Chr4:82146047-82248625 (-)
NOD/ShiLtJ ENSMUSG00190000878
 protein coding gene Chr4:77589368-77691955 (-)
NOD/ShiLtJ ENSMUSG00190000874
 protein coding gene Chr4:77586559-77590360 (-)
NZO/HlLtJ ENSMUSG00225004858
 protein coding gene Chr4:87254392-87258193 (-)
NZO/HlLtJ ENSMUSG00225004877
 protein coding gene Chr4:87257201-87359789 (-)
PWK/PhJ ENSLUMG00010001631
 protein coding gene Chr4:76845923-76948739 (-)
SPRET/EiJ ENSMSPG00010007567
 protein coding gene Chr4:78501548-78603557 (-)
WSB/EiJ ENSIUOG00005009416
 protein coding gene Chr4:77946670-78049223 (-)



Homology
more
  • Human Ortholog
    TTC39B, tetratricopeptide repeat domain 39B
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TTC39B, tetratricopeptide repeat domain 39B
  • Synonyms
    C9orf52
  • Links
    NCBI Gene ID: 158219
    UniProt: Q5VTQ0

  • Chr Location
    9p22.3; chr9:15163622-15307360 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    635
  • Tissues
    3
  • cDNA Data
    54
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 69863 NCBI Gene Model | MGI Sequence Detail 103952 C57BL/6J ±  kb
    transcript NM_027238 RefSeq | MGI Sequence Detail 8764 C57BL/6  
    polypeptide Q8BYY4 UniProt | EBI | MGI Sequence Detail 617 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 54
      cDNA 54

      Microarray probesets 10
    Other
    Accession IDs
    less
    MGI:1914069, MGI:2140292, MGI:2140529, MGI:2140564
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 2
      Gene Ontology 2
      Phenotypes 15
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:384092 Chen PB, et al., Complementation testing identifies genes mediating effects at quantitative trait loci underlying fear-related behavior. Cell Genom. 2024 May 8;4(5):100545
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory