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Rab43
Gene Detail
Symbol

Name
ID
Rab43
RAB43, member RAS oncogene family
MGI:1917084
Synonyms
1810048P08Rik, 2500004H21Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 6
39.13 cM, cytoband D2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr6:87788853-87812164 bp, - strand
From VEGA annotation of GRCm38

  23312 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:43122  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: RAB43
Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab43

Human
homologs
RAB43, RAB43, member RAS oncogene family
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 339122
neXtProt AC: NX_Q86YS6

Human Synonyms: RAB11B, RAB41

Human Chr (Location): 3q21.3; chr3:129087569-129122150 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(2) Spontaneous(1) Targeted(5)
Genomic Mutations involving Rab43 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Rab43 interacts with 301 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process Golgi organization, intracellular protein transport, ...
Component cytoplasmic vesicle, endosome, ...
Function GTPase activity, GTP binding, ...
External Resources: FuncBase
Expression
cDNA source data(66)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase rab43    NEW 
Molecular
reagents
All nucleic(66) cDNA(66)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000022164 (Evidence)
Ensembl Gene Model ENSMUSG00000030055 (Evidence)
Entrez Gene 69834 (Evidence)
UniGene 37380
DFCI TC1587760, TC1584876, TC1598745, TC1704489
DoTS DT.528674, DT.94297657, DT.101404199, DT.110489389, DT.101404197, DT.481794, DT.101310601
NIA Mouse Gene Index U027584
Consensus CDS Project CCDS20329.1, CCDS20330.1
International Mouse Phenotyping Consortium Status Rab43
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022164 VEGA Gene Model | MGI Sequence Detail 23312 C57BL/6J ±  kb
transcript OTTMUST00000052630 VEGA | MGI Sequence Detail 4605 Not Applicable 
polypeptide OTTMUSP00000024979 VEGA | MGI Sequence Detail 210 Not Applicable 

For the selected sequences
All sequences(68) RefSeq(7) UniProt(5)
Polymorphisms
SNPs within 2kb(58 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003579 Small GTPase superfamily, Rab type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013630 ras-related protein Rab-43
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:197389 Slater LH, et al., CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9932-7
All references(37)
Other
accession IDs
MGI:1917339, MGI:2141679

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory