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Rab43 Gene Detail
Summary
  • Symbol
    Rab43
  • Name
    RAB43, member RAS oncogene family
  • Synonyms
    1810048P08Rik, 2500004H21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917084
    NCBI Gene: 69834
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:87788853-87812164 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 39.13 cM, cytoband D2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    57 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917084
protein coding gene Chr6:87788853-87812164 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030998
protein coding gene Chr6:89153695-89180131 (-)
A/J MGP_AJ_G0030964
protein coding gene Chr6:85713200-85736592 (-)
AKR/J MGP_AKRJ_G0030895
protein coding gene Chr6:88192064-88215245 (-)
BALB/cJ MGP_BALBcJ_G0030977
protein coding gene Chr6:85708419-85731543 (-)
C3H/HeJ MGP_C3HHeJ_G0030733
protein coding gene Chr6:96256583-96279862 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031434
protein coding gene Chr6:91544976-91568252 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028617
protein coding gene Chr6:83885926-83909051 (-)
CAST/EiJ MGP_CASTEiJ_G0030086
protein coding gene Chr6:88272554-88295728 (-)
CBA/J MGP_CBAJ_G0030661
protein coding gene Chr6:95089369-95112603 (-)
DBA/2J MGP_DBA2J_G0030817
protein coding gene Chr6:85013179-85036487 (-)
FVB/NJ MGP_FVBNJ_G0030770
protein coding gene Chr6:84199847-84224005 (-)
LP/J MGP_LPJ_G0030894
protein coding gene Chr6:89170929-89198765 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030803
protein coding gene Chr6:99225707-99248832 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031461
protein coding gene Chr6:88045174-88068420 (-)
PWK/PhJ MGP_PWKPhJ_G0029801
protein coding gene Chr6:83981089-84004821 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029629
protein coding gene Chr6:86861073-86884204 (-)
WSB/EiJ MGP_WSBEiJ_G0030167
protein coding gene Chr6:88495108-88520104 (-)



Homology
more
  • Human Ortholog
    RAB43, RAB43, member RAS oncogene family
  • Vertebrate Orthologs
    8
  • Human Ortholog
    RAB43, RAB43, member RAS oncogene family
    Orthology source: HGNC, HomoloGene
  • Synonyms
    RAB11B, RAB41
  • Links
    NCBI Gene ID: 339122
    neXtProt AC: NX_Q86YS6
    UniProt: Q86YS6

  • Chr Location
    3q21.3; chr3:129087569-129122150 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit defects in dendritic cell antigen presentation.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 69834 NCBI Gene Model | MGI Sequence Detail 23312 C57BL/6J ±  kb
transcript NM_001039394 RefSeq | MGI Sequence Detail 4605 C57BL/6  
polypeptide Q8CG50 UniProt | EBI | MGI Sequence Detail 210 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 67
    cDNA 67

    Microarray probesets 5
Other
Accession IDs
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MGI:1917339, MGI:2141679
References
more
  • Summaries
    All 40
    Gene Ontology 7
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:246066 Sundberg JP, et al., Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program. PLoS One. 2017;12(7):e0180682

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory