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Rab43 Gene Detail
Summary
  • Symbol
    Rab43
  • Name
    RAB43, member RAS oncogene family
  • Synonyms
    1810048P08Rik, 2500004H21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917084
    NCBI Gene: 69834
Location & Maps
more
  • Sequence Map
    Chr6:87788853-87812164 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      23312 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 39.13 cM, cytoband D2
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    RAB43, RAB43, member RAS oncogene family
  • Vertebrate Orthologs
    8
  • Human Ortholog
    RAB43, RAB43, member RAS oncogene family
    Orthology source: HGNC, HomoloGene
  • Synonyms
    RAB11B, RAB41
  • Links
    NCBI Gene ID: 339122
    neXtProt AC: NX_Q86YS6

  • Chr Location
    3q21.3; chr3:129087569-129122150 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    6
  • Spontaneous
    1
  • Targeted
    5
  • Genomic Mutations
    1 involving Rab43
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022164 VEGA Gene Model | MGI Sequence Detail 23312 C57BL/6J ±  kb
transcript OTTMUST00000052630 VEGA | MGI Sequence Detail 4605 Not Applicable  
polypeptide OTTMUSP00000024979 VEGA | MGI Sequence Detail 210 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    57 from dbSNP Build 142
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000013630 ras-related protein Rab-43
  • InterPro Domains
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR001806 Small GTPase superfamily
    IPR005225 Small GTP-binding protein domain
Molecular
Reagents
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  • All nucleic 66
    cDNA 66

    Microarray probesets 5
Other
Accession IDs
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MGI:1917339, MGI:2141679
References
more
  • Summaries
    All 32
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:197389 Slater LH, et al., CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9932-7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory