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Prss32 Gene Detail
Summary
  • Symbol
    Prss32
  • Name
    serine protease 32
  • Synonyms
    2010001P08Rik, mT5, tryptase-5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917064
    NCBI Gene: 69814
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:24072746-24078750 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 17, 12.09 cM, cytoband A3.3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    240 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917064
protein coding gene Chr17:24062829-24078753 (+)
129S1/SvImJ ENSMUSG00200037291
protein coding gene Chr17:19481906-19497574 (+)
A/J ENSMUSG00195036536
protein coding gene Chr17:20510170-20516342 (+)
AKR/J ENSMUSG00220022887
protein coding gene Chr17:19570744-19576921 (+)
BALB/cJ ENSMUSG00180015997
protein coding gene Chr17:19793257-19799429 (+)
C3H/HeJ ENSMUSG00175033063
protein coding gene Chr17:19577768-19583945 (+)
C57BL/6NJ ENSMUSG00215040770
protein coding gene Chr17:19570565-19586527 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021165
protein coding gene Chr17:19684737-19690704 (+)
CAST/EiJ ENSTCUG00005022774
protein coding gene Chr17:20146152-20162256 (+)
CBA/J ENSMUSG00210034771
protein coding gene Chr17:19416582-19422759 (+)
DBA/2J ENSMUSG00185051802
protein coding gene Chr17:21598582-21604754 (+)
FVB/NJ ENSMUSG00205014938
protein coding gene Chr17:19867107-19873280 (+)
JF1/MsJ ENSUMUG00000056786
protein coding gene Chr17:21062354-21078325 (+)
LP/J ENSMUSG00230054945
protein coding gene Chr17:22996099-23002271 (+)
NOD/ShiLtJ ENSMUSG00190029582
protein coding gene Chr17:19495684-19501836 (+)
NZO/HlLtJ ENSMUSG00225053022
protein coding gene Chr17:24917714-24923886 (+)
PWK/PhJ ENSLUMG00010019718
protein coding gene Chr17:18958281-18974245 (+)
SPRET/EiJ ENSMSPG00010035800
protein coding gene Chr17:20328641-20334882 (+)
WSB/EiJ ENSIUOG00005036245
protein coding gene Chr17:20234591-20250215 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69814 NCBI Gene Model | MGI Sequence Detail 6005 C57BL/6J ±  kb
transcript NM_027220 RefSeq | MGI Sequence Detail 1460 Not Specified  
polypeptide NP_081496 RefSeq | MGI Sequence Detail 334 Not Specified  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • EC
  • InterPro Domains
    IPR001314 Peptidase S1A, chymotrypsin family
    IPR009003 Peptidase S1, PA clan
    IPR018114 Serine protease-like, trypsin family, histidine active site
    IPR001254 Serine proteases, trypsin domain
    IPR033116 Serine proteases, trypsin family, serine active site
Molecular
Reagents
less
  • All nucleic 64
    cDNA 63
    Primer pair 1

    Microarray probesets 5
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory