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Cox11 Gene Detail
Summary
  • Symbol
    Cox11
  • Name
    cytochrome c oxidase assembly protein 11, copper chaperone
  • Synonyms
    2010004I09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917052
    NCBI Gene: 69802
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr11:90638173-90644931 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      6759 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 55.45 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    COX11, cytochrome c oxidase copper chaperone COX11
  • Vertebrate Orthologs
    10
  • Human Ortholog
    COX11, cytochrome c oxidase copper chaperone COX11
    Orthology source: HGNC, HomoloGene
  • Synonyms
    COX11P
  • Links
    NCBI Gene ID: 1353
    neXtProt AC: NX_Q9Y6N1
    UniProt: Q9Y6N1

  • Chr Location
    17q22; chr17:54951898-54971024 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 3221
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: COX11
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001603 VEGA Gene Model | MGI Sequence Detail 6759 C57BL/6J ±  kb
transcript OTTMUST00000003126 VEGA | MGI Sequence Detail 1224 Not Applicable  
polypeptide OTTMUSP00000001511 VEGA | MGI Sequence Detail 275 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    68 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000005770 cytochrome c oxidase assembly protein COX11, mitochondrial
  • InterPro Domains
    IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11
    IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily
Molecular
Reagents
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  • All nucleic 50
    cDNA 49
    Primer pair 1

    Microarray probesets 5
References
more
  • Summaries
    All 38
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 5
    Phenotypes 12
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
09/11/2018
MGI 6.12
The Jackson Laboratory