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Aldh16a1 Gene Detail
Summary
  • Symbol
    Aldh16a1
  • Name
    aldehyde dehydrogenase 16 family, member A1
  • Synonyms
    2410004H02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916998
    NCBI Gene: 69748
  • Gene Overview
    MyGene.info: ALDH16A1
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:45141840-45154538 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 29.15 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    124 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916998
protein coding gene Chr7:45140684-45154584 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032203
protein coding gene Chr7:45375939-45389879 (-)
A/J MGP_AJ_G0032182
protein coding gene Chr7:44513287-44529709 (-)
AKR/J MGP_AKRJ_G0032118
protein coding gene Chr7:45743092-45758178 (-)
BALB/cJ MGP_BALBcJ_G0032194
protein coding gene Chr7:44512263-44526925 (-)
C3H/HeJ MGP_C3HHeJ_G0031910
protein coding gene Chr7:46230725-46253035 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032686
protein coding gene Chr7:47645492-47660894 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029700
protein coding gene Chr7:47076815-47090398 (-)
CAST/EiJ MGP_CASTEiJ_G0031238
protein coding gene Chr7:37625965-37641256 (-)
CBA/J MGP_CBAJ_G0031874
protein coding gene Chr7:49205843-49219551 (-)
DBA/2J MGP_DBA2J_G0032032
protein coding gene Chr7:44187143-44201172 (-)
FVB/NJ MGP_FVBNJ_G0031983
protein coding gene Chr7:43961837-43975851 (-)
LP/J MGP_LPJ_G0032110
protein coding gene Chr7:46058627-46073327 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032020
protein coding gene Chr7:47923331-47937050 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032702
protein coding gene Chr7:44959221-44974140 (-)
PWK/PhJ MGP_PWKPhJ_G0030961
protein coding gene Chr7:37550265-37564804 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030798
protein coding gene Chr7:32973397-32986921 (-)
WSB/EiJ MGP_WSBEiJ_G0031355
protein coding gene Chr7:45455151-45470231 (-)



Homology
more
  • Human Ortholog
    ALDH16A1, aldehyde dehydrogenase 16 family member A1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ALDH16A1, aldehyde dehydrogenase 16 family member A1
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 126133
    neXtProt AC: NX_Q8IZ83
    UniProt: Q8IZ83

  • Chr Location
    19q13.33; chr19:49453216-49471050 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69748 NCBI Gene Model | MGI Sequence Detail 12699 C57BL/6J ±  kb
transcript NM_145954 RefSeq | MGI Sequence Detail 2572 C57BL/6  
polypeptide Q571I9 UniProt | EBI | MGI Sequence Detail 802 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    7 Sequences
  • InterPro Domains
    IPR011408 Aldehyde dehydrogenase
    IPR016163 Aldehyde dehydrogenase, C-terminal
    IPR015590 Aldehyde dehydrogenase domain
    IPR016162 Aldehyde dehydrogenase, N-terminal
    IPR016161 Aldehyde/histidinol dehydrogenase
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 4
Other
Accession IDs
less
MGI:2141972
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:255311 Charkoftaki G, et al., Transcriptomic analysis and plasma metabolomics in Aldh16a1-null mice reveals a potential role of ALDH16A1 in renal function. Chem Biol Interact. 2017 Oct 1;276:15-22

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory