About   Help   FAQ
Aldh16a1 Gene Detail
Summary
  • Symbol
    Aldh16a1
  • Name
    aldehyde dehydrogenase 16 family, member A1
  • Synonyms
    2410004H02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916998
    NCBI Gene: 69748
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:44791257-44804008 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 29.15 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    125 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916998
 protein coding gene Chr7:44790108-44804008 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032203
 protein coding gene Chr7:45375939-45389879 (-)
A/J MGP_AJ_G0032182
 protein coding gene Chr7:44513287-44529709 (-)
AKR/J MGP_AKRJ_G0032118
 protein coding gene Chr7:45743092-45758178 (-)
BALB/cJ MGP_BALBcJ_G0032194
 protein coding gene Chr7:44512263-44526925 (-)
C3H/HeJ MGP_C3HHeJ_G0031910
 protein coding gene Chr7:46230725-46253035 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032686
 protein coding gene Chr7:47645492-47660894 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029700
 protein coding gene Chr7:47076815-47090398 (-)
CAST/EiJ MGP_CASTEiJ_G0031238
 protein coding gene Chr7:37625965-37641256 (-)
CBA/J MGP_CBAJ_G0031874
 protein coding gene Chr7:49205843-49219551 (-)
DBA/2J MGP_DBA2J_G0032032
 protein coding gene Chr7:44187143-44201172 (-)
FVB/NJ MGP_FVBNJ_G0031983
 protein coding gene Chr7:43961837-43975851 (-)
LP/J MGP_LPJ_G0032110
 protein coding gene Chr7:46058627-46073327 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032020
 protein coding gene Chr7:47923331-47937050 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032702
 protein coding gene Chr7:44959221-44974140 (-)
PWK/PhJ MGP_PWKPhJ_G0030961
 protein coding gene Chr7:37550265-37564804 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030798
 protein coding gene Chr7:32973397-32986921 (-)
WSB/EiJ MGP_WSBEiJ_G0031355
 protein coding gene Chr7:45455151-45470231 (-)



Homology
more
  • Human Ortholog
    ALDH16A1, aldehyde dehydrogenase 16 family member A1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ALDH16A1, aldehyde dehydrogenase 16 family member A1
  • Links
    NCBI Gene ID: 126133
    neXtProt AC: NX_Q8IZ83
    UniProt: Q8IZ83

  • Chr Location
    19q13.33; chr19:49453225-49471050 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 2 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous knockout mice exhibit abnormal blood plasma lipid and ion profiles.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    16
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 69748 NCBI Gene Model | MGI Sequence Detail 12752 C57BL/6J ±  kb
    transcript NM_145954 RefSeq | MGI Sequence Detail 2572 C57BL/6  
    polypeptide Q571I9 UniProt | EBI | MGI Sequence Detail 802 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 16
      cDNA 16

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2141972
    References
    more
    • Summaries
      All 34
      Developmental Gene Expression 1
      Gene Ontology 1
      Phenotypes 12
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:274872 Ingham NJ, et al., Mouse screen reveals multiple new genes underlying mouse and human hearing loss. PLoS Biol. 2019 Apr;17(4):e3000194
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory