Smyd3
Gene Detail

Symbol Name ID

Smyd3 SET and MYND domain containing 3 MGI:1916976

Synonyms

2410008A19Rik, Zmynd1

Feature Type

protein coding gene

Genetic Map

Chromosome 1

83.48 cM, cytoband H3
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr1:178951960-179518041 bp, - strand From VEGA annotation of GRCm38   566082 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:41491  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: protein methyltransferase, HSKM-B type
Gene Tree: Smyd3

Human homologs

Human Homolog		SMYD3, SET and MYND domain containing 3
NCBI Gene ID		64754
neXtProt AC		NX_Q9H7B4
Human Synonyms		bA74P14.1, KMT3E, ZMYND1, ZNFN3A1
Human Chr (Location)		1q44; chr1:245912642-246670644 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(33) : Targeted(5) Gene trapped(28)

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	chromatin modification, histone lysine methylation, ...
Component	cytoplasm, nucleus
Function	histone-lysine N-methyltransferase activity, metal ion binding, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (10)    Tissues (10)   
Theiler Stages: 22, 28

Assay Type	Results
Northern blot	10

cDNA source data(39)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(39) cDNA(39)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000017093 (Evidence)
Ensembl Gene Model	ENSMUSG00000055067 (Evidence)
Entrez Gene	69726 (Evidence)
UniGene	222338
DFCI	TC1579140, TC1588580
DoTS	DT.101710326, DT.523920, DT.91299334, DT.97409239
NIA Mouse Gene Index	U022132
EC	2.1.1.43
Consensus CDS Project	CCDS15560.1
International Mouse Knockout Project Status	Smyd3

Sequences

Length	Strain/Species
genomic	OTTMUSG00000017093	VEGA Gene Model | MGI Sequence Detail	566082	C57BL/6J
transcript	OTTMUST00000041394	VEGA | MGI Sequence Detail	6871	Not Applicable
polypeptide	OTTMUSP00000018573	VEGA | MGI Sequence Detail	428	Not Applicable

All sequences(45) RefSeq(2) UniProt(5)

Polymorphisms

SNPs(3180 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR025805	Histone-lysine N-methyltransferase Smyd3
InterPro	IPR001214	SET domain
InterPro	IPR002893	Zinc finger, MYND-type
Protein Ontology	PR:000015307	SET and MYND domain-containing protein 3

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)