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Rpain Gene Detail
Summary
  • Symbol
    Rpain
  • Name
    RPA interacting protein
  • Synonyms
    2400006N03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916973
    NCBI Gene: 69723
  • Gene Overview
    MyGene.info: RPAIN
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:70970213-70977833 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 43.21 cM, cytoband B4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    52 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916973
protein coding gene Chr11:70970200-70977933 (.)
129S1/SvImJ MGP_129S1SvImJ_G0018619
protein coding gene Chr11:71544487-71553319 (+)
A/J MGP_AJ_G0018587
protein coding gene Chr11:68826217-68833837 (+)
AKR/J MGP_AKRJ_G0018556
protein coding gene Chr11:70900692-70908313 (+)
BALB/cJ MGP_BALBcJ_G0018559
protein coding gene Chr11:69136455-69144076 (+)
C3H/HeJ MGP_C3HHeJ_G0018372
protein coding gene Chr11:70928540-70936161 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019010
protein coding gene Chr11:73713846-73721466 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016655
protein coding gene Chr11:65731138-65739251 (+)
CAST/EiJ MGP_CASTEiJ_G0017927
protein coding gene Chr11:71205401-71214723 (+)
CBA/J MGP_CBAJ_G0018344
protein coding gene Chr11:77034337-77041958 (+)
DBA/2J MGP_DBA2J_G0018454
protein coding gene Chr11:68406123-68413749 (+)
FVB/NJ MGP_FVBNJ_G0018444
protein coding gene Chr11:68049348-68056973 (+)
LP/J MGP_LPJ_G0018524
protein coding gene Chr11:72124220-72133494 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018467
protein coding gene Chr11:77575578-77583199 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019052
protein coding gene Chr11:71158580-71166201 (+)
PWK/PhJ MGP_PWKPhJ_G0017701
protein coding gene Chr11:69057685-69068022 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017491
protein coding gene Chr11:70967296-70975499 (+)
WSB/EiJ MGP_WSBEiJ_G0017981
protein coding gene Chr11:70821873-70829495 (+)



Homology
more
  • Human Ortholog
    RPAIN, RPA interacting protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RPAIN, RPA interacting protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HRIP, RIP
  • Links
    NCBI Gene ID: 84268
    neXtProt AC: NX_Q86UA6
    UniProt: Q86UA6

  • Chr Location
    17p13.2; chr17:5419185-5433020 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 13006
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: RPAIN
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000018449 Ensembl Gene Model | MGI Sequence Detail 7621 C57BL/6J ±  kb
transcript ENSMUST00000018593 Ensembl | MGI Sequence Detail 1100 Not Applicable  
polypeptide ENSMUSP00000018593 Ensembl | MGI Sequence Detail 219 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 35
    cDNA 35

    Microarray probesets 4
References
more
  • Summaries
    All 35
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory