About   Help   FAQ
Nkiras1 Gene Detail
Summary
  • Symbol
    Nkiras1
  • Name
    NFKB inhibitor interacting Ras-like protein 1
  • Synonyms
    2400004O09Rik, KBRAS1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916971
    NCBI Gene: 69721
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:18271136-18284003 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 7.08 cM, cytoband A3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    122 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916971
protein coding gene Chr14:18271136-18284003 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021020
protein coding gene Chr14:10881412-10895322 (+)
A/J MGP_AJ_G0020969
protein coding gene Chr14:10566671-10579617 (+)
AKR/J MGP_AKRJ_G0020946
protein coding gene Chr14:10882794-10896820 (+)
BALB/cJ MGP_BALBcJ_G0020972
protein coding gene Chr14:10629537-10641457 (+)
C3H/HeJ MGP_C3HHeJ_G0020756
protein coding gene Chr14:10964324-10976423 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021405
protein coding gene Chr14:11274269-11290687 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018974
protein coding gene Chr14:11071308-11088216 (+)
CAST/EiJ MGP_CASTEiJ_G0020279
protein coding gene Chr14:10828444-10840864 (+)
CBA/J MGP_CBAJ_G0020722
protein coding gene Chr14:11749833-11766221 (+)
DBA/2J MGP_DBA2J_G0020845
protein coding gene Chr14:10466874-10479570 (+)
FVB/NJ MGP_FVBNJ_G0020828
protein coding gene Chr14:10337103-10349991 (+)
LP/J MGP_LPJ_G0020921
protein coding gene Chr14:10948842-10959427 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020854
protein coding gene Chr14:11630440-11649757 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021437
protein coding gene Chr14:10765575-10780121 (+)
PWK/PhJ MGP_PWKPhJ_G0020030
protein coding gene Chr14:10527304-10539699 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019850
protein coding gene Chr14:10897236-10909297 (+)
WSB/EiJ MGP_WSBEiJ_G0020335
protein coding gene Chr14:10813389-10831668 (+)



Homology
more
  • Human Ortholog
    NKIRAS1, NFKB inhibitor interacting Ras like 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    NKIRAS1, NFKB inhibitor interacting Ras like 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    kappaB-Ras1, KBRAS1
  • Links
    NCBI Gene ID: 28512
    neXtProt AC: NX_Q9NYS0
    UniProt: Q9NYS0

  • Chr Location
    3p24.2; chr3:23889536-23917046 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69721 NCBI Gene Model | MGI Sequence Detail 12868 C57BL/6J ±  kb
transcript NM_001316711 RefSeq | MGI Sequence Detail 4868 Not Specified  
polypeptide Q8CEC5 UniProt | EBI | MGI Sequence Detail 192 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 41
    cDNA 41

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/13/2019
MGI 6.13
The Jackson Laboratory