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Ipmk
Gene Detail
Symbol

Name
ID
Ipmk
inositol polyphosphate multikinase
MGI:1916968
Synonyms
2410017C19Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 10
36.89 cM, cytoband B5.2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr10:71347763-71433327 bp, + strand
From VEGA annotation of GRCm38

  85565 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:76214  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: IPMK
Gene Tree: Ipmk

Human
homologs
IPMK, inositol polyphosphate multikinase
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 253430
neXtProt AC: NX_Q8NFU5

Human Chr (Location): 10q21.1; chr10:58191517-58267937 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(24) : Gene trapped(17) Targeted(7)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Homozygous null mice display embryonic lethality, reduced embryo size, delayed embryonic development, failure of chorioallantoic fusion and embryo turning, and a kinked and open neural tube.
 
Phenotype Images(1)
Interactions
Ipmk interacts with 321 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process inositol phosphate biosynthetic process, neural tube formation, ...
Component nucleolus, nucleoplasm, ...
Function ATP binding, inositol-1,4,5-trisphosphate 3-kinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (24)    Tissues (18)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 24
cDNA source data(100)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ipmk    NEW 
Molecular
reagents
All nucleic(104) cDNA(103) Other(1)
Microarray probesets(7)
Other database
links
VEGA Gene Model OTTMUSG00000031016 (Evidence)
Ensembl Gene Model ENSMUSG00000060733 (Evidence)
Entrez Gene 69718 (Evidence)
UniGene 245867
DFCI TC1660597, TC1598343, TC1591917, TC1583296
DoTS DT.531717, DT.40134074, DT.101257164, DT.110583371, DT.101185420, DT.94167230
NIA Mouse Gene Index U011643
EC 2.7.1.151
Consensus CDS Project CCDS23918.1
International Mouse Phenotyping Consortium Status Ipmk
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031016 VEGA Gene Model | MGI Sequence Detail 85565 C57BL/6J ±  kb
transcript OTTMUST00000076826 VEGA | MGI Sequence Detail 1492 Not Applicable 
polypeptide OTTMUSP00000040504 VEGA | MGI Sequence Detail 397 Not Applicable 

For the selected sequences
All sequences(71) RefSeq(7) UniProt(3)
Polymorphisms
SNPs within 2kb(389 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005522 Inositol polyphosphate kinase
Protein Ontology PR:000009084 inositol polyphosphate multikinase
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:203053 Kim E, et al., Inositol polyphosphate multikinase is a coactivator for serum response factor-dependent induction of immediate early genes. Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19938-43
All references(41)
Other
accession IDs
MGI:2143463

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory