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Trip13 Gene Detail
Summary
  • Symbol
    Trip13
  • Name
    thyroid hormone receptor interactor 13
  • Synonyms
    2410002G23Rik, D13Ertd328e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916966
    NCBI Gene: 69716
  • Gene Overview
    MyGene.info: TRIP13
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr13:73911347-73937767 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      26421 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 40.15 cM, cytoband C1
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    TRIP13, thyroid hormone receptor interactor 13
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TRIP13, thyroid hormone receptor interactor 13
    Orthology source: HomoloGene, HGNC
  • Synonyms
    16E1BP, MVA3
  • Links
    NCBI Gene ID: 9319
    neXtProt AC: NX_Q15645
    UniProt: Q15645

  • Chr Location
    5p15.33; chr5:892854-919348 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    34 phenotypes from 3 alleles in 2 genetic backgrounds
    2 images
    22 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trapped allele exhibit postnatal lethality, infertility, reduced gonad size, tail defects and meiotic arrest of sperm and oocytes associated with unrepaired double strand breaks.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000054943 VEGA Gene Model | MGI Sequence Detail 26421 C57BL/6J ±  kb
    transcript OTTMUST00000136177 VEGA | MGI Sequence Detail 3382 Not Applicable  
    polypeptide OTTMUSP00000071946 VEGA | MGI Sequence Detail 432 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      157 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 11
      Primer pair 4

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1196282
    References
    more
    • Summaries
      All 54
      Developmental Gene Expression 6
      Gene Ontology 6
      Phenotypes 22
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:253200 Rinaldi VD, et al., The DNA Damage Checkpoint Eliminates Mouse Oocytes with Chromosome Synapsis Failure. Mol Cell. 2017 Sep 21;67(6):1026-1036.e2

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    05/15/2018
    MGI 6.12
    The Jackson Laboratory