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Aarsd1 Gene Detail
Summary
  • Symbol
    Aarsd1
  • Name
    alanyl-tRNA synthetase domain containing 1
  • Synonyms
    2310044P18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916934
    NCBI Gene: 69684
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:101406665-101417433 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 64.95 cM, cytoband D
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    37 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916934
protein coding gene Chr11:101406665-101417615 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019199
protein coding gene Chr11:104264813-104275394 (-)
A/J MGP_AJ_G0019167
protein coding gene Chr11:99883440-99893891 (-)
AKR/J MGP_AKRJ_G0019136
protein coding gene Chr11:102991332-103001725 (-)
BALB/cJ MGP_BALBcJ_G0019141
protein coding gene Chr11:100377845-100389743 (-)
C3H/HeJ MGP_C3HHeJ_G0018950
protein coding gene Chr11:103160025-103171214 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019590
protein coding gene Chr11:107540716-107553134 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017216
protein coding gene Chr11:97285935-97297442 (-)
CAST/EiJ MGP_CASTEiJ_G0018504
protein coding gene Chr11:104145715-104158393 (-)
CBA/J MGP_CBAJ_G0018919
protein coding gene Chr11:111973467-111986684 (-)
DBA/2J MGP_DBA2J_G0019031
protein coding gene Chr11:99405216-99417453 (-)
FVB/NJ MGP_FVBNJ_G0019021
protein coding gene Chr11:98952962-98963529 (-)
LP/J MGP_LPJ_G0019100
protein coding gene Chr11:104811996-104822528 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019052
protein coding gene Chr11:111531130-111543165 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019628
protein coding gene Chr11:103314195-103330657 (-)
PWK/PhJ MGP_PWKPhJ_G0018267
protein coding gene Chr11:100467214-100483901 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018059
protein coding gene Chr11:103041019-103055657 (-)
WSB/EiJ MGP_WSBEiJ_G0018553
protein coding gene Chr11:103316264-103328509 (-)



Homology
more
  • Human Ortholog
    AARSD1, alanyl-tRNA synthetase domain containing 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    AARSD1, alanyl-tRNA synthetase domain containing 1
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 80755
    neXtProt AC: NX_Q9BTE6
    UniProt: Q9BTE6

  • Chr Location
    17q21.31; chr17:42950526-42964498 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 69684 NCBI Gene Model | MGI Sequence Detail 10769 C57BL/6J ±  kb
transcript NM_144829 RefSeq | MGI Sequence Detail 1346 FVB/N  
polypeptide Q3THG9 UniProt | EBI | MGI Sequence Detail 412 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR018165 Alanyl-tRNA synthetase, class IIc, core domain
    IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal
    IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily
    IPR012947 Threonyl/alanyl tRNA synthetase, SAD
    IPR009000 Translation protein, beta-barrel domain superfamily
Molecular
Reagents
less
  • All nucleic 93
    cDNA 93

    Microarray probesets 2
Other
Accession IDs
less
MGI:2144034
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:236196 Echeverria PC, et al., A Remodeled Hsp90 Molecular Chaperone Ensemble with the Novel Cochaperone Aarsd1 Is Required for Muscle Differentiation. Mol Cell Biol. 2016 Apr;36(8):1310-21

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory