Upk3bl MGI Mouse Gene Detail - MGI:1916915

Symbol

Upk3bl
Name

uroplakin 3B-like
Synonyms

2310043J07Rik

Feature Type

protein coding gene
IDs

MGI:1916915
NCBI Gene: 69665
Alliance

gene page
Transcription Start Sites

10 TSS

Sequence Map

Chr5:136083346-136093180 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 5, 75.72 cM, cytoband G1
Mapping Data

2 experiments

SNPs within 2kb

857 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1916915	protein coding gene	Chr5:136083346-136105549 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0030198	protein coding gene	Chr5:140668046-140679188 (+)
A/J	MGP_AJ_G0030166	protein coding gene	Chr5:134617615-134627441 (+)
AKR/J	MGP_AKRJ_G0030099	protein coding gene	Chr5:138970087-138980084 (+)
BALB/cJ	MGP_BALBcJ_G0030176	protein coding gene	Chr5:135973291-135983721 (+)
C3H/HeJ	MGP_C3HHeJ_G0029892	protein coding gene	Chr5:139584297-139594062 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0030629	protein coding gene	Chr5:145898199-145908950 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0027849	protein coding gene	Chr5:128906089-128916187 (+)
CAST/EiJ	MGP_CASTEiJ_G0029302	protein coding gene	Chr5:138981407-138991151 (+)
CBA/J	MGP_CBAJ_G0029862	protein coding gene	Chr5:151590455-151603599 (+)
DBA/2J	MGP_DBA2J_G0030013	protein coding gene	Chr5:134519145-134529078 (+)
FVB/NJ	MGP_FVBNJ_G0029968	protein coding gene	Chr5:133672474-133682274 (+)
LP/J	MGP_LPJ_G0030102	protein coding gene	Chr5:141094675-141106779 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0030000	protein coding gene	Chr5:154577840-154589574 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0030669	protein coding gene	Chr5:138778349-138789514 (+)
PWK/PhJ	MGP_PWKPhJ_G0029015	protein coding gene	Chr5:133580795-133590813 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0028851	protein coding gene	Chr5:136320502-136329920 (+)
WSB/EiJ	MGP_WSBEiJ_G0029375	protein coding gene	Chr5:139503836-139514922 (+)

Human Ortholog

UPK3BL1, uroplakin 3B like 1

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

UPK3BL1, uroplakin 3B like 1
Synonyms

UPK3BL, UPLP
Links

HGNC:37278

NCBI Gene ID: 100134938

neXtProt AC: NX_B0FP48, NX_E5RIL1

UniProt: B0FP48
Chr Location

chr7:102637025-102642791 (-) GRCh38

Human Ortholog

UPK3BL2, uroplakin 3B like 2
Links

HGNC:53444

NCBI Gene ID: 107983993

UniProt: E5RIL1
Chr Location

chr7:102537919-102543696 (-) GRCh38

MGI Vertebrate Homology

Upk3bl stringent orthology
2 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: UPK3BL1, UPK3BL2
Gene Tree

Upk3bl

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Phenotype Summary

2 phenotype references

All Mutations and Alleles

5
Gene trapped

5
Incidental Mutations

APF
Find Mice (IMSR)

16 strains or lines available

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All GO Annotations

7
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

747
Tissues

34
cDNA Data

15
Literature Summary

1

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

50
RefSeq

10
UniProt

5
CCDS

CCDS51665.1

Ensembl

ENSMUSG00000006143 (Evidence)
NCBI Gene

69665

			Length	Strain/Species	Flank
genomic	ENSMUSG00000006143	Ensembl Gene Model \| MGI Sequence Detail	9835	C57BL/6J	± kb
transcript	ENSMUST00000111137	Ensembl \| MGI Sequence Detail	1119	Not Applicable
polypeptide	ENSMUSP00000106767	Ensembl \| MGI Sequence Detail	314	Not Applicable

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UniProt

5 Sequences
InterPro Domains

IPR010255 Haem peroxidase superfamily

IPR024831 Uroplakin-3
GlyGen

Q9D701 3 sites

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All nucleic 15

cDNA 15

Microarray probesets 2

Summaries

All 23

Developmental Gene Expression 1

Gene Ontology 5

Phenotypes 2
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14

TSS for Upk3bl:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr49216	Chr5:136083322-136083329 (+)	-20 bp
Tssr49217	Chr5:136085977-136085985 (+)	2,635 bp
Tssr49218	Chr5:136085992-136085997 (+)	2,649 bp
Tssr49219	Chr5:136086141-136086152 (+)	2,801 bp
Tssr49220	Chr5:136086158-136086200 (+)	2,833 bp
Tssr49221	Chr5:136086202-136086216 (+)	2,863 bp
Tssr1671	Chr5:136088880-136088890 (+)	5,539 bp
Tssr49222	Chr5:136088891-136088906 (+)	5,553 bp
Tssr49223	Chr5:136088909-136088940 (+)	5,579 bp
Tssr49224	Chr5:136088942-136088956 (+)	5,603 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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