About   Help   FAQ
Tmbim1
Gene Detail
Symbol

Name
ID
Tmbim1
transmembrane BAX inhibitor motif containing 1
MGI:1916910
Synonyms
2310061B02Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 1
38.53 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:74288247-74305622 bp, - strand
From VEGA annotation of GRCm38

  17376 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:36404  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: TMBIM1
Protein SuperFamily: glutamate binding protein 1, vertebrate type
Gene Tree: Tmbim1

Human
homologs
TMBIM1, transmembrane BAX inhibitor motif containing 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 64114
neXtProt AC: NX_Q969X1

Human Synonyms: LFG3, MST100, MSTP100, PP1201, RECS1

Human Chr (Location): 2q35; chr2:218274194-218292557 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(15) : Gene trapped(12) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit susceptibility to cystic medial degeneration without inflammation or change in blood pressure and are prone to aortic dilation with age.
 
Interactions
Tmbim1 interacts with 178 markers (Mir1b, Mir7-1, Mir7-2, ...)
Expression
Literature Summary: (1 records)
Data Summary: Results (12)    Tissues (4)    Images (10)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 12
cDNA source data(15)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase tmbim1 ; ZFIN tmbim1    NEW 
Molecular
reagents
All nucleic(15) cDNA(15)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000021738 (Evidence)
Ensembl Gene Model ENSMUSG00000006301 (Evidence)
Entrez Gene 69660 (Evidence)
DFCI TC1641113, TC1778369, TC1572374, TC1591594
DoTS DT.110949874, DT.94178506, DT.91430705, DT.110949914, DT.91308423, DT.87072689
Consensus CDS Project CCDS15044.1
International Mouse Phenotyping Consortium Status Tmbim1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021738 VEGA Gene Model | MGI Sequence Detail 17376 C57BL/6J ±  kb
transcript OTTMUST00000051568 VEGA | MGI Sequence Detail 2378 Not Applicable 
polypeptide OTTMUSP00000024302 VEGA | MGI Sequence Detail 309 Not Applicable 

For the selected sequences
All sequences(79) RefSeq(6) UniProt(8)
Polymorphisms
SNPs within 2kb(82 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006214 Bax inhibitor 1-related
Protein Ontology PR:000029594 protein lifeguard 3
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)
Other
accession IDs
MGI:2138482, MGI:2138674, MGI:2146371

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/23/2015
MGI 5.22
The Jackson Laboratory