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Arhgap27 Gene Detail
Summary
  • Symbol
    Arhgap27
  • Name
    Rho GTPase activating protein 27
  • Synonyms
    2310069I04Rik, 5730442P18Rik, Sh3d20
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916903
    NCBI Gene: 544817
  • Alliance
    genome feature page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:103222323-103254518 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 67.02 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    984 from dbSNP Build 142
  • Strain Annotations
    28
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916903
 protein coding gene Chr11:103222310-103254518 (-)
129S1/SvImJ ENSMUSGG00200054991
 protein coding gene Chr11:100508359-100533261 (-)
129S1/SvImJ ENSMUSG00200051646
 protein coding gene Chr11:100536627-100537806 (-)
A/J ENSMUSG00195049946
 protein coding gene Chr11:100236081-100237260 (-)
A/J ENSMUSGG00195055528
 protein coding gene Chr11:100207800-100221020 (-)
AKR/J ENSMUSG00220047172
 protein coding gene Chr11:100444827-100446006 (-)
AKR/J ENSMUSGG00220054942
 protein coding gene Chr11:100416542-100429763 (-)
BALB/cJ ENSMUSG00180051713
 protein coding gene Chr11:100583331-100584510 (-)
BALB/cJ ENSMUSGG00180055638
 protein coding gene Chr11:100555053-100568267 (-)
C3H/HeJ ENSMUSG00175039787
 protein coding gene Chr11:100510209-100511388 (-)
C3H/HeJ ENSMUSGG00175055185
 protein coding gene Chr11:100481947-100495150 (-)
C57BL/6NJ ENSMUSGG00215055831
 protein coding gene Chr11:100045011-100069898 (-)
C57BL/6NJ ENSMUSG00215053301
 protein coding gene Chr11:100073262-100074441 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017279
 protein coding gene Chr11:99291494-99323539 (-)
CAST/EiJ no annotation
CBA/J ENSMUSGG00210055136
 protein coding gene Chr11:100183592-100208508 (-)
CBA/J ENSMUSG00210053165
 protein coding gene Chr11:100211872-100213051 (-)
DBA/2J ENSMUSG00185049473
 protein coding gene Chr11:100560007-100561186 (-)
DBA/2J ENSMUSGG00185057990
 protein coding gene Chr11:100531739-100544944 (-)
FVB/NJ ENSMUSG00205045797
 protein coding gene Chr11:100394956-100396135 (-)
FVB/NJ ENSMUSGG00205054707
 protein coding gene Chr11:100366661-100391582 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230032755
 protein coding gene Chr11:101612396-101613575 (-)
LP/J ENSMUSGG00230055498
 protein coding gene Chr11:101584138-101597337 (-)
NOD/ShiLtJ ENSMUSG00190049144
 protein coding gene Chr11:100591522-100592701 (-)
NOD/ShiLtJ ENSMUSGG00190055134
 protein coding gene Chr11:100563256-100576466 (-)
NZO/HlLtJ ENSMUSG00225049167
 protein coding gene Chr11:103627852-103629031 (-)
NZO/HlLtJ ENSMUSGG00225055580
 protein coding gene Chr11:103599577-103612790 (-)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPGG00010052243
 protein coding gene Chr11:100813543-100825721 (-)
WSB/EiJ ENSIUOGG00005053854
 protein coding gene Chr11:100325705-100350600 (-)



Homology
more
  • Human Ortholog
    ARHGAP27, Rho GTPase activating protein 27
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ARHGAP27, Rho GTPase activating protein 27
  • Synonyms
    CAMGAP1, PP905, SH3D20, SH3P20
  • Links
    NCBI Gene ID: 201176
    UniProt: Q6ZUM4

  • Chr Location
    17q21.31; chr17:45393898-45434421 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    731
  • Tissues
    23
  • cDNA Data
    12
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034255 Ensembl Gene Model | MGI Sequence Detail 32196 C57BL/6J ±  kb
transcript ENSMUST00000107024 Ensembl | MGI Sequence Detail 4261 Not Applicable  
polypeptide ENSMUSP00000102639 Ensembl | MGI Sequence Detail 869 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    Genomic 2
    cDNA 14

    Microarray probesets 4
Other
Accession IDs
less
MGI:1917809
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 9
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:183631 Tossidou I, et al., CD2AP regulates SUMOylation of CIN85 in podocytes. Mol Cell Biol. 2012 Mar;32(6):1068-79
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory