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Sec24d Gene Detail
Summary
  • Symbol
    Sec24d
  • Name
    Sec24 related gene family, member D (S. cerevisiae)
  • Synonyms
    2310020L09Rik, LOC383951
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916858
    NCBI Gene: 69608
  • Gene Overview
    MyGene.info: SEC24D
Location & Maps
more
  • Sequence Map
    Chr3:123267455-123365641 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      98187 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 53.82 cM, cytoband G3
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    SEC24D, SEC24 homolog D, COPII coat complex component
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SEC24D, SEC24 homolog D, COPII coat complex component
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CLCRP2
  • Links
    NCBI Gene ID: 9871
    neXtProt AC: NX_O94855
    UniProt: O94855

  • Chr Location
    4q26; chr4:118722823-118838683 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human SEC24D associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 3 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit early embryonic lethality. A hypomorphic gene trap allele results in lethality during organogenesis.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000052539 VEGA Gene Model | MGI Sequence Detail 98187 C57BL/6J ±  kb
transcript OTTMUST00000131727 VEGA | MGI Sequence Detail 3903 Not Applicable  
polypeptide OTTMUSP00000070376 VEGA | MGI Sequence Detail 1032 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1187 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 71
    cDNA 70
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2686195
References
more
  • Summaries
    All 33
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:239648 Bettigole SE, et al., The transcription factor XBP1 is selectively required for eosinophil differentiation. Nat Immunol. 2015 Aug;16(8):829-37

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/12/2017
MGI 6.10
The Jackson Laboratory