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Sec24d Gene Detail
Summary
  • Symbol
    Sec24d
  • Name
    Sec24 related gene family, member D (S. cerevisiae)
  • Synonyms
    2310020L09Rik, LOC383951
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916858
    NCBI Gene: 69608
  • Gene Overview
    MyGene.info: SEC24D
Location & Maps
more
  • Sequence Map
    Chr3:123267455-123365641 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      98187 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 53.82 cM, cytoband G3
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    SEC24D, SEC24 homolog D, COPII coat complex component
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SEC24D, SEC24 homolog D, COPII coat complex component
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CLCRP2
  • Links
    NCBI Gene ID: 9871
    neXtProt AC: NX_O94855

  • Chr Location
    4q26; chr4:118722823-118838683 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human SEC24D associations

Human Disease Mouse Models
       Cole-Carpenter Syndrome 2; CLCRP2   OMIM: 616294
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 3 alleles in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    1
  • Gene trapped
    5
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    2 involving Sec24d
  • Incidental Mutations
Mice homozygous for a knock-out allele exhibit early embryonic lethality. A hypomorphic gene trap allele results in lethality during organogenesis.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000052539 VEGA Gene Model | MGI Sequence Detail 98187 C57BL/6J ±  kb
transcript OTTMUST00000131727 VEGA | MGI Sequence Detail 3903 Not Applicable  
polypeptide OTTMUSP00000070376 VEGA | MGI Sequence Detail 1032 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1187 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 71
    cDNA 70
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2686195
References
more
  • Summaries
    All 28
    Developmental Gene Expression 4
    Gene Ontology 1
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:214959 Lodato S, et al., Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons. Nat Neurosci. 2014 Aug;17(8):1046-54

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory