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Mtfmt Gene Detail
Summary
  • Symbol
    Mtfmt
  • Name
    mitochondrial methionyl-tRNA formyltransferase
  • Synonyms
    2310020P08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916856
    NCBI Gene: 69606
  • Gene Overview
    MyGene.info: MTFMT
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:65435782-65453054 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 35.31 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    104 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916856
protein coding gene Chr9:65435782-65453054 (.)
129S1/SvImJ MGP_129S1SvImJ_G0034959
protein coding gene Chr9:65169180-65188416 (+)
A/J MGP_AJ_G0034939
protein coding gene Chr9:62972535-62990648 (+)
AKR/J MGP_AKRJ_G0034869
protein coding gene Chr9:64465306-64482580 (+)
BALB/cJ MGP_BALBcJ_G0034932
protein coding gene Chr9:62696104-62713565 (+)
C3H/HeJ MGP_C3HHeJ_G0034642
protein coding gene Chr9:64993228-65011028 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035451
protein coding gene Chr9:66951228-66970564 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032362
protein coding gene Chr9:62621072-62639731 (+)
CAST/EiJ MGP_CASTEiJ_G0033963
protein coding gene Chr9:65176996-65194087 (+)
CBA/J MGP_CBAJ_G0034613
protein coding gene Chr9:69294300-69314457 (+)
DBA/2J MGP_DBA2J_G0034772
protein coding gene Chr9:62742728-62760278 (+)
FVB/NJ MGP_FVBNJ_G0034714
protein coding gene Chr9:62067094-62084856 (+)
LP/J MGP_LPJ_G0034855
protein coding gene Chr9:65448229-65465301 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034756
protein coding gene Chr9:70508344-70530862 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035473
protein coding gene Chr9:64563015-64581279 (+)
PWK/PhJ MGP_PWKPhJ_G0033667
protein coding gene Chr9:62947334-62965586 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033501
protein coding gene Chr9:64847358-64867943 (+)
WSB/EiJ MGP_WSBEiJ_G0034076
protein coding gene Chr9:64468671-64485891 (+)



Homology
more
  • Human Ortholog
    MTFMT, mitochondrial methionyl-tRNA formyltransferase
  • Vertebrate Orthologs
    9
  • Human Ortholog
    MTFMT, mitochondrial methionyl-tRNA formyltransferase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    COXPD15, FMT1
  • Links
    NCBI Gene ID: 123263
    neXtProt AC: NX_Q96DP5
    UniProt: Q96DP5

  • Chr Location
    15q22.31; chr15:65001512-65029639 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human MTFMT associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69606 NCBI Gene Model | MGI Sequence Detail 17273 C57BL/6J ±  kb
transcript NM_027134 RefSeq | MGI Sequence Detail 2042 C57BL/6  
polypeptide Q9D799 UniProt | EBI | MGI Sequence Detail 386 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 31
    cDNA 31

    Microarray probesets 4
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:239776 Arguello T, et al., Cre recombinase activity is inhibited in vivo but not ex vivo by a mutation in the asymmetric spacer region of the distal loxP site. Genesis. 2015 Nov;53(11):695-700

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory