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Plekhm2
Gene Detail
 Symbol
Name
ID
Plekhm2
pleckstrin homology domain containing, family M (with RUN domain) member 2
MGI:1916832
Synonyms 2310034J19Rik
Feature Type protein coding gene
Genetic Map
Chromosome 4
74.64 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:141625734-141664899 bp, - strand
From VEGA annotation of GRCm38

  39166 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:19575  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Plekhm2

Human
homologs
Human Homolog PLEKHM2, pleckstrin homology domain containing, family M (with RUN domain) member 2
NCBI Gene ID 23207
neXtProt AC  NX_Q8IWE5
Human Synonyms  SKIP
Human Chr (Location)  1p36.21; chr1:15684137-15734769 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Plekhm2 interacts with 121 markers (Mir24-1, Mir24-2, Mir29a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process Golgi organization
Component cytoplasm
Function kinesin binding
External Resources: FuncBase
Expression
cDNA source data(52)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(52) cDNA(52)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000010343 (Evidence)
Ensembl Gene ModelENSMUSG00000028917 (Evidence)
Entrez Gene69582 (Evidence)
UniGene33220
DFCITC1601041, TC1602774, TC1637663
DoTSDT.101703962, DT.110807111, DT.94275331, DT.97403766, DT.97412619
NIA Mouse Gene IndexU025729
Consensus CDS ProjectCCDS51348.1
International Mouse Knockout Project StatusPlekhm2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000010343 VEGA Gene Model | MGI Sequence Detail 39166 C57BL/6J ±  kb
transcript OTTMUST00000024092 VEGA | MGI Sequence Detail 4136 Not Applicable 
polypeptide OTTMUSP00000011061 VEGA | MGI Sequence Detail 1033 Not Applicable 

For the selected sequences
All sequences(53) RefSeq(5) UniProt(3)
Polymorphisms SNPs within 2kb(419 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001849 Pleckstrin homology domain
InterPro IPR011993 Pleckstrin homology-like domain
InterPro IPR004012 RUN
Protein Ontology PR:000031600 pleckstrin homology domain-containing family M member 2
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)
Other
accession IDs
MGI:2140397

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory