Plekhm2
Gene Detail

Symbol Name ID

Plekhm2 pleckstrin homology domain containing, family M (with RUN domain) member 2 MGI:1916832

Synonyms

2310034J19Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 4

74.64 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr4:141625734-141664899 bp, - strand From VEGA annotation of GRCm38   39166 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:19575  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Plekhm2

Human homologs

Human Homolog		PLEKHM2, pleckstrin homology domain containing, family M (with RUN domain) member 2
NCBI Gene ID		23207
neXtProt AC		NX_Q8IWE5
Human Synonyms		SKIP
Human Chr (Location)		1p36.21; chr1:15684137-15734769 (+)  GRCh38

Alleles and phenotypes

All alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )

Gene Ontology (GO) classifications

All GO classifications: (3 annotations)

Process	Golgi organization
Component	cytoplasm
Function	kinesin binding

External Resources: FuncBase

Expression

cDNA source data(52)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(52) cDNA(52)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000010343 (Evidence)
Ensembl Gene Model	ENSMUSG00000028917 (Evidence)
Entrez Gene	69582 (Evidence)
UniGene	33220
DFCI	TC1601041, TC1602774, TC1637663
DoTS	DT.101703962, DT.110807111, DT.94275331, DT.97403766, DT.97412619
NIA Mouse Gene Index	U025729
Consensus CDS Project	CCDS51348.1
International Mouse Knockout Project Status	Plekhm2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000010343	VEGA Gene Model | MGI Sequence Detail	39166	C57BL/6J
transcript	OTTMUST00000024092	VEGA | MGI Sequence Detail	4136	Not Applicable
polypeptide	OTTMUSP00000011061	VEGA | MGI Sequence Detail	1033	Not Applicable

All sequences(53) RefSeq(5) UniProt(3)

Polymorphisms

SNPs within 2kb(419 from dbSNP Build 137)

Protein-related information

Resource	ID	Description
InterPro	IPR001849	Pleckstrin homology domain
InterPro	IPR011993	Pleckstrin homology-like domain
InterPro	IPR004012	RUN
Protein Ontology	PR:000031600	pleckstrin homology domain-containing family M member 2

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)

Other accession IDs

MGI:2140397