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Rhou Gene Detail
Summary
  • Symbol
    Rhou
  • Name
    ras homolog family member U
  • Synonyms
    2310026M05Rik, Arhu, CDC42L1, mG28K, WRCH1, WRCH-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916831
    NCBI Gene: 69581
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:123653929-123663880 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 72.10 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    43 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916831
protein coding gene Chr8:123653929-123663884 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034260
protein coding gene Chr8:127265143-127275083 (+)
A/J MGP_AJ_G0034240
protein coding gene Chr8:122031866-122042070 (+)
AKR/J MGP_AKRJ_G0034167
protein coding gene Chr8:125537095-125547217 (+)
BALB/cJ MGP_BALBcJ_G0034233
protein coding gene Chr8:122211340-122221987 (+)
C3H/HeJ MGP_C3HHeJ_G0033944
protein coding gene Chr8:126172278-126183327 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034753
protein coding gene Chr8:131549203-131559183 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031695
protein coding gene Chr8:114812171-114822076 (+)
CAST/EiJ MGP_CASTEiJ_G0033272
protein coding gene Chr8:126276148-126286045 (+)
CBA/J MGP_CBAJ_G0033917
protein coding gene Chr8:136349484-136359445 (+)
DBA/2J MGP_DBA2J_G0034073
protein coding gene Chr8:121185161-121195145 (+)
FVB/NJ MGP_FVBNJ_G0034017
protein coding gene Chr8:120341558-120351980 (+)
LP/J MGP_LPJ_G0034163
protein coding gene Chr8:127437163-127447098 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034064
protein coding gene Chr8:138496244-138506253 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034772
protein coding gene Chr8:125763903-125773856 (+)
PWK/PhJ MGP_PWKPhJ_G0032973
protein coding gene Chr8:120925154-120935634 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032813
protein coding gene Chr8:124405748-124421207 (+)
WSB/EiJ MGP_WSBEiJ_G0033388
protein coding gene Chr8:126492945-126502885 (+)



Homology
more
  • Human Ortholog
    RHOU, ras homolog family member U
  • Vertebrate Orthologs
    8
  • Human Ortholog
    RHOU, ras homolog family member U
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ARHU, CDC42L1, G28K, hG28K, WRCH1
  • Links
    NCBI Gene ID: 58480
    neXtProt AC: NX_Q7L0Q8
    UniProt: Q7L0Q8

  • Chr Location
    1q42.13; chr1:228644647-228746669 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 69581 NCBI Gene Model | MGI Sequence Detail 9952 C57BL/6J ±  kb
    transcript NM_133955 RefSeq | MGI Sequence Detail 3367 Not Specified  
    polypeptide Q9EQT3 UniProt | EBI | MGI Sequence Detail 261 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 72
      cDNA 70
      Primer pair 1
      Other 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:2142472
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 6
      Gene Ontology 5
      Phenotypes 4
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:229484 Conte D, et al., The apical ectodermal ridge of the mouse model of ectrodactyly Dlx5;Dlx6-/- shows altered stratification and cell polarity, which are restored by exogenous Wnt5a ligand. Hum Mol Genet. 2016 Feb 15;25(4):740-54

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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    last database update
    10/08/2019
    MGI 6.14
    The Jackson Laboratory