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Mfsd3 Gene Detail
Summary
  • Symbol
    Mfsd3
  • Name
    major facilitator superfamily domain containing 3
  • Synonyms
    2310010G13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916822
    NCBI Gene: 69572
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:76701542-76704239 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 36.28 cM, cytoband E1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    26 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916822
protein coding gene Chr15:76701465-76704239 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022008
protein coding gene Chr15:76803632-76806329 (+)
A/J MGP_AJ_G0021966
protein coding gene Chr15:73988829-73991526 (+)
AKR/J MGP_AKRJ_G0021949
protein coding gene Chr15:75997426-76000123 (+)
BALB/cJ MGP_BALBcJ_G0021975
protein coding gene Chr15:74014593-74017290 (+)
C3H/HeJ MGP_C3HHeJ_G0021747
protein coding gene Chr15:76044712-76047409 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022415
protein coding gene Chr15:79664799-79667496 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019944
protein coding gene Chr15:70647940-70650645 (+)
CAST/EiJ MGP_CASTEiJ_G0021266
protein coding gene Chr15:76851001-76853698 (+)
CBA/J MGP_CBAJ_G0021714
protein coding gene Chr15:82186445-82189142 (+)
DBA/2J MGP_DBA2J_G0021839
protein coding gene Chr15:73527118-73529815 (+)
FVB/NJ MGP_FVBNJ_G0021819
protein coding gene Chr15:72585094-72587791 (+)
LP/J MGP_LPJ_G0021910
protein coding gene Chr15:76884745-76887442 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021844
protein coding gene Chr15:87533984-87536681 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022435
protein coding gene Chr15:76272046-76274743 (+)
PWK/PhJ MGP_PWKPhJ_G0021007
protein coding gene Chr15:73692381-73695955 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020847
protein coding gene Chr15:75967986-75970675 (+)
WSB/EiJ MGP_WSBEiJ_G0021318
protein coding gene Chr15:76363317-76366014 (+)



Homology
more
  • Human Ortholog
    MFSD3, major facilitator superfamily domain containing 3
  • Vertebrate Orthologs
    7
  • Human Ortholog
    MFSD3, major facilitator superfamily domain containing 3
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 113655
    neXtProt AC: NX_Q96ES6
    UniProt: Q96ES6

  • Chr Location
    8q24.3; chr8:144508081-144511228 (+)  GRCh38.p7

Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    26 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    3
  • Gene trapped
    3
  • Radiation induced
    2
  • Targeted
    2
  • Genomic Mutations
    5 involving Mfsd3
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 69572 NCBI Gene Model | MGI Sequence Detail 2698 C57BL/6J ±  kb
transcript NM_027122 RefSeq | MGI Sequence Detail 2169 C57BL/6  
polypeptide Q5U419 UniProt | EBI | MGI Sequence Detail 412 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • InterPro Domains
    IPR004752 AmpG-like permease/Acetyl-coenzyme A transporter 1
    IPR011701 Major facilitator superfamily
    IPR036259 MFS transporter superfamily
Molecular
Reagents
less
  • All nucleic 17
    cDNA 17

    Microarray probesets 3
References
more
  • Summaries
    All 46
    Diseases 1
    Gene Ontology 4
    Phenotypes 26
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory