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Vkorc1l1 Gene Detail
Summary
  • Symbol
    Vkorc1l1
  • Name
    vitamin K epoxide reductase complex, subunit 1-like 1
  • Synonyms
    2310024K08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916818
    NCBI Gene: 69568
Location & Maps
more
  • Sequence Map
    Chr5:129941970-129986692 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      44723 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 68.26 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    VKORC1L1, vitamin K epoxide reductase complex subunit 1 like 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    VKORC1L1, vitamin K epoxide reductase complex subunit 1 like 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 154807
    neXtProt AC: NX_Q8N0U8

  • Chr Location
    7q11.21; chr7:65836336-65959563 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    69
  • Chemically induced (other)
    1
  • Gene trapped
    66
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Vkorc1l1
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000055677 VEGA Gene Model | MGI Sequence Detail 44723 C57BL/6J ±  kb
transcript OTTMUST00000137796 VEGA | MGI Sequence Detail 3112 Not Applicable  
polypeptide OTTMUSP00000072526 VEGA | MGI Sequence Detail 176 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    184 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 5
References
more
  • Summaries
    All 29
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:207800 Hammed A, et al., VKORC1L1, an enzyme rescuing the vitamin K 2,3-epoxide reductase activity in some extrahepatic tissues during anticoagulation therapy. J Biol Chem. 2013 Oct 4;288(40):28733-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory