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Klhdc2
Gene Detail
 Symbol
Name
ID
Klhdc2
kelch domain containing 2
MGI:1916804
Synonyms 2310022K15Rik, D12Ertd522e, HCLP-1
Feature Type protein coding gene
Genetic Map
Chromosome 12
28.77 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr12:69296681-69310687 bp, + strand
From VEGA annotation of GRCm38

  14007 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8631  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Klhdc2

Human
homologs
Human Homolog KLHDC2, kelch domain containing 2
NCBI Gene ID 23588
neXtProt AC  NX_Q9Y2U9
Human Synonyms  HCLP1, HCLP-1, LCP
Human Chr (Location)  14q21.3; chr14:49767589-49785622 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(2) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Klhdc2 interacts with 131 markers (Mir15a, Mir22, Mir23a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process biological_process
Component nucleus
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (91)    Tissues (14)    Images (23)
Theiler Stages: 23
Assay TypeResults
RNA in situ 91
cDNA source data(130)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(134) cDNA(133) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000023685 (Evidence)
Ensembl Gene ModelENSMUSG00000020978 (Evidence)
Entrez Gene69554 (Evidence)
UniGene234368
DFCITC1574912, TC1591770
NIA Mouse Gene IndexU043286
Consensus CDS ProjectCCDS25950.1
International Mouse Knockout Project StatusKlhdc2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023685 VEGA Gene Model | MGI Sequence Detail 14007 C57BL/6J ±  kb
transcript OTTMUST00000058026 VEGA | MGI Sequence Detail 1905 Not Applicable 
polypeptide OTTMUSP00000028061 VEGA | MGI Sequence Detail 406 Not Applicable 

For the selected sequences
All sequences(31) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(187 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011043 Galactose oxidase/kelch, beta-propeller
InterPro IPR015915 Kelch-type beta propeller
Protein Ontology PR:000009370 kelch domain-containing protein 2
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(38)
Other
accession IDs
MGI:1261874

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory