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Bst2 Gene Detail
Summary
  • Symbol
    Bst2
  • Name
    bone marrow stromal cell antigen 2
  • Synonyms
    2310015I10Rik, Bst-2, C87040, GREG
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916800
    NCBI Gene: 69550
Location & Maps
more
  • Sequence Map
    Chr8:71534264-71537437 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3174 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 34.43 cM
  • Mapping Data
    2 experiments
Homology
less
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Targeted
    3
  • Genomic Mutations
    1 involving Bst2
  • Incidental Mutations
Mice homozygous for a knock-out allele exhibit increased susceptibility to the LP-BM5 strain of Mo-MLV (murine AIDS).
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000046718 Ensembl Gene Model | MGI Sequence Detail 3174 C57BL/6J ±  kb
transcript ENSMUST00000051672 Ensembl | MGI Sequence Detail 764 Not Applicable  
polypeptide ENSMUSP00000051921 Ensembl | MGI Sequence Detail 172 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    37 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000001326 bone marrow stromal antigen 2
  • PDB
  • InterPro Domains
    IPR024886 Bone marrow stromal antigen 2
Molecular
Reagents
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  • All nucleic 46
    cDNA 46

    Microarray probesets 2
Other
Accession IDs
less
MGI:2142879
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory